阿托伐他汀联合曲美他嗪治疗冠心病心绞痛患者的临床效果

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Abstract Objective To investigate the clinical effect of Atorvastatin combined with Trimetazidine in the treatment of angina pectoris patients with coronary heart disease. Methods A total of 100 patients with coronary heart disease and angina pectoris admitted to our hospital from January 2018 to March 2019 were selected as the research objects.According to different treatment schemes, they were divided into the experimental group (50 cases) and the control group(50 cases).The experimental group was treated with Atorvastatin combined with Trimetazidine, while the control group was treated with Trimetazidine.The treatment effect, blood lipid levels before and after treatment, angina pectoris frequency and duration were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the control group, and the difference was statistically significant (P＜0.05).The levels of lowdensity lipoprotein cholesterol (LDL-C), triglyceride (TG) and total cholesterol (TC) in the two groups after treatment were lower than those before treatment, and the levels of high-density lipoprotein cholesterol (HDL-C) in the two groups were higher than those before treatment, with statistically significant differences (P＜0.05).After treatment, the levels of LDL-C, TG and TC in the experimental group were lower than those in the control group, and the level of HDL-C was higher than that in the control group, with statistically significant differences (P＜0.05).After treatment, the number of angina attacks in the two groups was fewer than that before treatment, and the attack time was shorter than that before treatment, with statistically significant differences (P＜0.05).After treatment, the number of angina attacks in the experimental group was fewer than that in the control group, and the duration of the attacks was shorter than that in the control group, with statistically significant differences (P＜0.05). Conclusion Patients with coronary heart disease and angina pectoris receive Atorvastatin and Trimetazidine in combination, the effect is good, and it can improve the blood lipid treated with of patients.

Key words： Atorvastatin Trimetazidine Coronary heart disease Angina pectoris

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	ZHENG Xi

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ZHENG Xi. Clinical effect of Atorvastatin combined with Trimetazidine in the treatment of angina pectoris of coronary heart disease[J]. 中国当代医药, 2020, 27(15): 56-58转62.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I15/56

[1]	刘媛.阿托伐他汀联合曲美他嗪治疗冠心病的临床效果及其对心绞痛发作情况的影响分析[J].中国实用医药，2018，13（27）：86-87.
[2]	陈慧敏，许逸飞.曲美他嗪联合阿托伐他汀钙治疗冠心病心绞痛伴血脂异常的临床研究[J].中国临床药理学杂志，2016，32（11）：966-968.
[3]	马明.不同剂量阿托伐他汀钙联合曲美他嗪治疗冠心病心绞痛伴血脂异常的临床效果[J].临床医学研究与实践，2019，4（3）：39-41.
[4]	Athyros VG，Papageorgiou AA，Mercouris BR，et al.Treatment with atorvastatin to the National Cholesterol Educational Program goal versus "usual" care in secondary coronary heart disease prevention.The GREek Atorvastatin and Coronary-heart-disease evaluation (GREACE) study[J].Curr Med Res Opin，2002，18（4）：220-228.
[5]	崔自慧.冠心病患者应用阿托伐他汀联合曲美他嗪治疗的临床疗效分析[J].中国现代药物应用，2016，10（2）：173-174.
[6]	中华医学会心血管病学分会介入心脏病学组，中华医学会心血管病学分会动脉粥样硬化与冠心病学组，中国医师协会心血管内科医师分会血栓防治专业委员会，等.稳定性冠心病诊断与治疗指南[J].中华心血管病杂志，2018，46（9）：680-694.
[7]	马悦，马峰.阿托伐他汀钙联合曲美他嗪在冠心病心绞痛伴血脂异常患者中的应用效果[J].临床医学研究与实践，2019，4（24）：31-33.
[8]	余萍，厉莎莎，蒋利真，等.曲美他嗪、阿托伐他汀钙、心理干预联用治疗冠心病心绞痛伴血脂异常的临床研究[J].中国生化药物杂志，2017，37（9）：143-145.
[9]	杜建军，张红霞，马巧红，等.阿托伐他汀与曲美他嗪对冠心病患者血脂水平变化及心绞痛改善情况分析[J].中国生化药物杂志，2016，36（12）：57-59.
[10]	刘科.曲美他嗪、阿托伐他汀联合使用对冠心病不稳定型心绞痛的治疗效果观察[J].医药前沿，2018，8（2）：50-51.
[11]	刘永东，高亢.阿托伐他汀联合曲美他嗪治疗冠心病的临床疗效[J].中国循证心血管医学杂志，2016，8（3）：370-371，376.
[12]	王鲁奇.阿托伐他汀与曲美他嗪治疗冠心病的效果分析[J].中国急救医学，2016，36（Z1）：124-125.
[13]	黄守莲.阿托伐他汀联合曲美他嗪在冠心病患者的多靶点治疗效果分析[J].陕西医学杂志，2016，45（12）：1669-1670.
[14]	朱苑芳，王军.曲美他嗪治疗稳定型心绞痛临床疗效观察[J].心脑血管病防治，2016，16（1）：40-42.
[15]	毛静，秦曙光，梁志静，等.阿托伐他汀联合曲美他嗪治疗冠心病的效果[J].临床医学研究与实践，2019，4（4）：27-30.
[16]	王国华，李秋凤，蔡惠娜，等.曲美他嗪联合大剂量阿托伐他汀钙治疗不稳定性心绞痛的效果[J].中国当代医药，2019，26（9）：127-129，132.
[17]	黄幼艺.阿托伐他汀钙联合曲美他嗪治疗冠状动脉硬化性心脏病稳定性心绞痛的临床效果[J].中国当代医药，2018，25（31）：53-55.
[18]	宋国良.曲美他嗪与阿托伐他汀治疗冠心病心绞痛的效果[J].中国现代医生，2019，57（2）：41-43.