α1-微球蛋白、C-反应蛋白、D-二聚体检测在妊娠期高血压疾病诊疗中的应用价值

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Abstract Objective To explore the application value of combined detection of alpha 1-microglobulin (α1-MG), Creactive protein (CRP) and D-dimer (D-D) in the diagnosis and treatment of hypertensive disorder of pregnancy pregnancy. Methods A total of 63 patients with gestational hypertension treated in our hospital from December 2017 to December 2018 were selected as the study group, and 63 normal pregnant women were selected as the control group.The contents of α1-MG and CRP in serum of the two groups were determined by automatic biochemical analyzer. The content of D-D in plasma of the patients was determined by automatic hemagglutinometer. The contents of α1-MG,CRP and D-D in the two groups were compared. Results The levels of α1-MG, CRP and D-D in the study group were higher than those in the control group, with statistical differences (P＜0.05). The levels of α1-MG, CRP and D-D in patients with eclampsia were higher than those in patients with severe pre-eclampsia and patients with mild preeclampsia, and the levels of α1-MG, CRP and D-D in patients with severe pre-eclampsia were higher than those in patients with mild pre-eclampsia (P＜0.05). Conclusion α1-MG, CRP and D-D in patients with hypertensive disorder of pregnancy have a significant increase trend. α1-MG CRP and D-D levels in pregnant women can provide reference for the diagnosis of gestational hypertension, which is worthy to be widely used in clinical practice.

Key words： Alpha 1-microglobulin C-reactive protein D- dimer Hypertensive disorder of pregnancy

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	YU Fen-wei
	WU Wen-rong

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YU Fen-wei,WU Wen-rong. Application value of alpha 1- microglobulin, C- reactive protein and Ddimer in diagnosis and treatment of hypertensive disorder of pregnancy pregnancy[J]. 中国当代医药, 2020, 27(6): 177-179.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I6/177

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