喹硫平辅助治疗抑郁症睡眠障碍的临床效果

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Abstract Objective To study the clinical effect of Quintiapine in the treatment of sleep disorder in depression.Methods A total of 99 inpatients with depression complicated with sleep disorder treated in the Third People′s Hospital of Ji′an City from January 2017 to January 2019 were selected as the subjects,and divided into experimental group(33 cases,treated with Quintiapine)and control group 1(33 cases,treated with Eszopiclone)and control group 2(33 cases,treated with Alprazolam).The depression(Hamilton depression scale),sleep quality improvement(Pittsburgh sleep quality index scale),adverse reactions(drug side effects scale)and clinical treatment effect among the three groups were compared before and after treatment.Results There was no significant difference in the scores of depression,sleep quality and adverse reactions among the three groups before treatment(P＞0.05).After treatment,the scores of depression and sleep quality in the experimental group were lower than those in the control group 1 and control group 2,the differences were statistically significant(P＜0.05).There was no significant difference in the scores of adverse reactions among the three groups(P＞0.05).The total effective rate of clinical treatment in the experimental group was higher than that in the control group 1 and control group 2,the difference was statistically significant(P＜0.05).Conclusion Quintiapine is effective in the treatment of depressive sleep disorders,and can actively improve sleep quality and depression.

Key words： Quintiapine Eszopiclone Alprazolam Sleep disorder in depression

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	Articles by authors
	ZHU Fu-lai
	SUN Bin
	LI Ya-kun

Cite this article:

ZHU Fu-lai,SUN Bin,LI Ya-kun. Clinical effect of Quintiapine in the treatment of sleep disorder in depression[J]. 中国当代医药, 2020, 27(10): 60-62转70.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I10/60

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