奥沙利铂+替吉奥化疗联合滋阴健脾祛瘀汤对晚期胃癌患者疗效、生活质量及免疫学指标的影响

Abstract
Figure/Table
References (15)
Related Citation (6)

Download: PDF (0 KB) HTML (32 KB)
Export: BibTeX | EndNote (RIS)

Abstract ObjectiveTo analyze the influence of Oxaliplatin+Tegafur chemotherapy combined with Ziyin Jianpi Quyu Decoction on therapeutic effect,quality of life,and immunological indexes in patients with advanced gastric cancer.MethodsFrom January 2014 to January 2017,44 patients with advanced gastric cancer treated in our hospital were enrolled.By randomized integrated and sequent therapy,they were eveny divided into control group and observation group,and there were 22 cases in each group.Both groups were provided with Oxaliplatin and Tegafur.In the observation group,Ziyin Jianpi Quyu Decoction was added besides.The therapeutic effective rate,score of quality of life,and immunological indexes were compared between the two groups.ResultsThe therapeutic effective rate in the observation group was higher than that in the control group (P＜0.05).The indexes of physiological factor and social relation from QOLBREF scale in the observation group were superior to those in the control group (P＜0.05).After therapy,the indexes of CD4+and CD3+were both better than those in the control group with statistical differences(P＜0.05).ConclusionIn the treatment of advanced gastric cancer,application of Oxaliplatin+Tegafur chemotherapy combined with Ziyin Jianpi Quyu Decoction can improve the quality of life,immune function,as well as therapeutic effect,and reduce the toxic and side effects,which is worthy of clinical promotion.

Key words： Oxaliplatin Tegafur Ziyin Jianpi Quyu Decoction Gastric cancer

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZOU Cai-liang
	WANG Hong-yun
	WU Yan-ling
	XIA Xiao-long

Cite this article:

ZOU Cai-liang,WANG Hong-yun,WU Yan-ling, et al. Influence of Oxaliplatin+Tegafur chemotherapy combined with Ziyin Jianpi Quyu Decoction on therapeutic effect,quality of life,and immunological indexes in patients with advanced gastric cancer[J]. 中国当代医药, 2017, 24(32): 136-138.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I32/136

[1]	屈涛，杨林，张弘纲，等.不同剂量奥沙利铂联合替吉奥方案对晚期胃癌患者血小板的影响[J].中华结直肠疾病电子杂志，2017，6（1）：37-40.
[2]	陈洪盛.老年胃癌采取根治性全胃切除手术的效果[J].中国医学创新，2016，13（24）：123-125.
[3]	宋仲洁.替吉奥联合奥沙利铂化疗方案治疗老年晚期胃癌的临床研究[J].癌症进展，2016，14（2）：162-164.
[4]	卫生部.中国常见恶性肿瘤诊治规范[M].北京：北京医科大学、中国协和医科大学联合出版社，1991.
[5]	高丽娜.中医内科学[M].太原：山西科技出版社，2015.
[6]	张萍，艾斌.实体瘤免疫治疗疗效评价标准[J].国际肿瘤学杂志，2016，43（11）：848-851.
[7]	刘云军，何志江，黄毅超，等.替吉奥联合奥沙利铂对晚期胃癌患者TAM、CEA、CA72-4的影响[J].实用癌症杂志，2014，30（5）：506-508.
[8]	石萌.联合使用替吉奥和奥沙利铂对老年晚期胃癌患者进行化疗的效果探析[J].当代医药论丛，2015，5（17）：175-176.
[9]	汪质良，崔海忠，潘军武.奥沙利铂联合替吉奥对胃癌患者术后辅助化疗的效果及不良反应的研究[J].医学综述，2015，12（12）：2281-2283.
[10]	唐焕峰，吕炳涛.滋阴健脾祛瘀汤联合奥沙利铂、替吉奥对晚期胃癌患者生活质量及免疫学指标的影响[J].河北中医，2016，38（5）：675-678.
[11]	谢文健，闵江，钱昆，等.多西他赛或伊立替康联合奥沙利铂及替吉奥治疗晚期胃癌的临床疗效及安全性分析[J].重庆医学，2017，46（19）：2644-2648.
[12]	冯志刚.四君子汤联合奥沙利铂注射液加替吉奥方案治疗晚期胃癌的临床观察[J].内蒙古中医药，2014，33（36）：38-39.
[13]	赵晓宁，薛文翰.健脾化瘀方联合化疗治疗晚期胃癌疗效及对生活质量的影响[J].中医药学报，2016，44（3）：105-108.
[14]	杨林，宋岩，秦琼，等.替吉奥联合奥沙利铂一线治疗晚期胃癌的疗效和安全性[J].肿瘤防治研究，2013，40（7）：688-692.
[15]	秦晓纲.加减补中益气汤联合奥沙利铂、替吉奥方案治疗晚期胃癌随机对照临床研究[J].实用中医内科杂志，2012，27（14）：39-41.