|
|
Clinical effect of endoscopic submucosal dissection in the treatment of laterally spreading tumor |
ZENG De-hui WANG Fu-qun WANG Sheng-bing |
Department of Gastroenterology,People′s Hospital of Meizhou City in Guangdong Province,Meizhou 514031,China |
|
|
Abstract Objective To investigate the clinical effect of endoscopic submucosal dissection (ESD) in the treatment of lateral large intestine tumors.Methods Ninety patients with laterally spreading tumor treated in Meizhou People′s Hospital of Guangdong Province from January 2015 to May 2018 were selected as the subjects,and divided into control group (45 cases) and observation group (45 cases) by random number table method.The control group was treated with endoscopic mucosal resection (EMR),and the observation group was treated with ESD.Both groups were followed up for 12 months.The surgical indexes,incidence of complications and recurrence rate were compared between the two groups.Results There was no significant difference in intraoperative blood loss between the two groups (P>0.05).The whole resection rate and complete resection rate in the observation group were higher than those in the control group,the differences were statistically significant (P<0.05).The incidence of bleeding,intestinal perforation and wound infection was lower than that of the control group,the difference was statistically significant (P<0.05).There was no significant difference in the recurrence rate at 6 months after operation (P>0.05).The recurrence rate in the observation group was lower than that in the control group at 12 months after operation,the difference was statistically significant(P<0.05).Conclusion ESD for the treatment of laterally spreading tumor has less trauma,and the rate of complete resection and complete resection is better than EMR,and the recurrence rate is low,and the incidence of complications is not increased.It is worth promoting.
|
|
|
|
|
[12] |
韩梅,李蓥,詹婧,等.结直肠肿瘤内镜黏膜下剥离术完整切除及手术时间的影响因素分析[J].中华消化内镜杂志,2017,34(2):122-126.
|
[1] |
吴伟丹,王依,李永连.内镜黏膜下剥离术治疗结直肠侧向发育型肿瘤的护理[J].护士进修杂志,2017,32(14):224-225.
|
[2] |
Qi ZP,Shi Q,Liu JZ,et al.Efficacy and safety of endoscopic submucosal dissection for submucosal tumors of the colon and rectum[J].Gastrointest Endosc,2017,87(2):S001651071 7323271.
|
[3] |
李振,苏宏,吴冬,等.环周预切开内镜下黏膜切除术与内镜黏膜下剥离术治疗大肠侧向发育型肿瘤的效果分析[J].临床外科杂志,2018,26(12):85-87.
|
[4] |
贾婷婷,夏满奎,郭慧敏,等.内镜黏膜下剥离术治疗巨大直肠侧向发育型肿瘤的临床研究[J].中华消化内镜杂志,2018,35(7):531-534.
|
[5] |
梁丽,于妍斐,张继新,等.113例早期结直肠癌及癌前病变内镜粘膜下剥离术标本处理及病理学评估[J].中华消化内镜杂志,2018,35(7):511-517.
|
[6] |
吴杰,霍继荣,王东,等.Wnt及整合素信号通路在大肠侧向发育型肿瘤中的表达及与其内镜形态学之间的关系[J].南方医科大学学报,2017,37(9):98-105.
|
[7] |
Kudou M,Shiozaki A,Fujiwara H,et al.Efficacy of additional surgical resection after endoscopic submucosal dissection for superficial esophageal cancer[J].Anticancer Res,2017,37(9):5301.
|
[8] |
王华秀,练晶晶,陈世耀,等.内镜黏膜下剥离术治疗巨大结直肠侧向发育型肿瘤的临床研究[J].中国内镜杂志,2017,23(7):80-84.
|
[9] |
张其德,韩树堂,贺亚敏,等.内镜隧道技术在结直肠大面积侧向发育型肿瘤黏膜下剥离术中的临床应用[J].中华消化内镜杂志,2017,34(9):634.
|
[10] |
肖君,韩树堂.口袋法内镜黏膜下剥离术切除升结肠侧向发育型肿瘤一例(含视频)[J].中华消化内镜杂志,2017,34(7):515-516.
|
[11] |
刘宇洋,龚伟,黄思霖.美沙拉嗪栓预防直肠下段侧向发育型肿瘤内镜下环周黏膜下剥离术后狭窄一例[J].中华消化内镜杂志,2017,34(5):367-368.
|
[13] |
王雪萍,刘一品.快速康复护理在大肠侧向发育型肿瘤切除术后肠功能恢复中的应用效果[J].中华现代护理杂志,2018,24(14):1681-1684.
|
[14] |
钟选芳,张晓慧,甘爱华,等.c-Myc、p53和Ki-67 在不同形态的大肠侧向发育型肿瘤中的意义[J].江苏医药,2017,43(3):171-173.
|
[15] |
王双平,王桂周.内镜下黏膜分片切除术治疗结肠巨大侧向发育型腺瘤性息肉26例临床分析[J].安徽医药,2017,21(8):1456-1459.
|
|
|
|