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| Clinical effect of minimally invasive catheterization combined with Urokinase infusion in the treatment of cerebellar hemorrhage |
| WU Shi-qiang LUO An-lin FANG Ting GUAN Hui-dong LI Wen-tian |
| Department of Neurosurgery,Yangchun People′s Hospital,Guangdong Province,Yangchun 529600,China |
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Abstract Objective To observe the clinical effect of minimally invasive catheterization combined with Urokinase infusion in the treatment of cerebellar hemorrhage.Methods Fifty patients with cerebellar hemorrhage admitted to our hospital from January 2016 to December 2018 were enrolled in the study,and they were divided into the reference group (n=25) and the experimental group (n=25) according to the hidden number random method.The reference group was treated with conservative medical methods,and the experimental group was treated with minimally invasive catheterization combined with Urokinase infusion.The Glasgow coma scale (GCS) and national institute of health stroke scale (NIHSS) were used to evaluate the short-term efficacy before treatment and 2 weeks after treatment.The duration of coma,hospital stay and incidence of complications were compared between the two groups.All patients were followed up for 6 months,and activity of daily living (ADL) was used to evaluate the prognosis of patients.Results The NIHSS scores at 2 weeks after treatment in the two groups were lower than those at admission,and the GCS scores were higher than those at admission,with statistically significant differences (P＜0.05).The NIHSS score at 2 weeks after treatment in the experimental group was lower than that in the reference group,and the GCS score was higher than that in the reference group,with statistically significant differences (P＜0.05).There was no significant difference in the duration of coma between the two groups (P＞0.05).The hospital stay in the experimental group was shorter than that in the reference group,and the total incidence rate of complications was lower than that in the reference group,with statistically significant differences (P＜0.05).After 6 months of follow-up,the good prognosis rate of the experimental group was 64.00%,which was higher than that of the reference group accounting for 52.00%,and the difference was statistically significant (P＜0.05).Conclusion Minimally invasive catheterization combined with Urokinase infusion for cerebellar hemorrhage is an easy,rapid,safe and effective treatment.
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