创伤性颅脑损伤患者预后的影响因素分析

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Abstract Objective To analyze the influential factors of prognosis in patients with traumatic brain injury and provide scientific basis for clinical decision-making.Methods The clinical data of 67 patients with traumatic brain injury admitted to Heilongjiang Provincial Hospital from April to July 2018 were retrospectively analyzed,they were divided into good prognosis groups (37 cases) and poor prognosis group (30 cases) according to the prognosis of 3 months after discharge and different Glasgow prognosis grade (GOS).Univariate and multivariate of clinical influencing factors of prognosis in patients with traumatic brain injury were analysed.The prediction ability of Logistic regression model was evaluated by receiver operating characteristic (ROC) curve,area under the curve (AUC),sensitivity and specificity.Results Univariate analysis showed that the age,hematoma volume,blood glucose,white blood cell and neutrophil counts of the poor prognosis group were higher than those of the good prognosis group,and the Glasgow coma score (GCS) and blood calcium level at the first diagnosis were lower than those of the good prognosis group,the differences were statistically significant (P＜0.05).Multivariate Logistic regression analysis showed that the first diagnosis of GCS (β=-0.367,OR=0.693,95%CI=0.554-0.867) score was a protective factor for poor prognosis in patients with traumatic brain injury.White blood cell count (β=0.249,OR=1.283,95%CI=1.053-1.562) was an independent risk factor for poor prognosis in patients with traumatic brain injury (P＜0.05).Regression model AUC was 0.906,sensitivity and specificity were 93.3%and 83.8%,respectively.Conclusion The first diagnosis of GCS score and white blood cell count are independent related factors that affect the prognosis of patients with traumatic brain injury.Clinically detectable levels of the two have important significance for the prognosis of patients with brain injury.

Key words： Traumatic brain injury Influencing factors Prognosis Glasgow prognosis scale

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	Articles by authors
	SUN Guo-zhang
	JIANG Feng-ling
	LI Ying
	MA Bo-wen
	LIU Ting
	TAO Yu

Cite this article:

SUN Guo-zhang,JIANG Feng-ling,LI Ying, et al. Analysis of influential factors of prognosis in patients with traumatic brain injury[J]. 中国当代医药, 2020, 27(5): 50-52转56.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I5/50

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