肺保护性通气治疗严重胸部创伤并发急性呼吸窘迫综合征的临床效果及对通气功能的影响

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Abstract Objective To investigate the clinical effect of pulmonary protective ventilation in patients with severe chest trauma complicated by acute respiratory distress syndrome (ARDS).Methods In this study,66 patients with severe chest trauma complicated with ARDS admitted to ICU from April 2016 to April 2019 were selected as subjects and divided into control group (33 cases) and observation group (33 cases) according to the random number table method.The control group received routine ventilation and conventional treatment,the observation group was given lung protective ventilation treatment.The clinical efficacy,blood gas analysis indicators before and after ventilation,assisted ventilation time and mortality of the two groups were compared.Results The total clinical efficiency of the patients in the observation group was higher than that of the control group,and the difference was statistically significant (P＜0.05).The values of oxygen partial pressure (PaO2),carbon dioxide partial pressure (PaCO2),and oxygen index (PaO2/FiO2) were compared between the two groups of patients with no statistical significance (P＞0.05).After 8 and 24hof ventilation,PaO2 and PaO2/FiO2 of two groups were higher than those before ventilation,and PaCO2 was lower than that before ventilation,the differences were statistically significant (P＜0.05).The PaO2 and PaO2/FiO2 after 8 and 24hof ventilation in the observation group were higher than those in the control group,and PaCO2 was lower than that in the control group,and the differences were statistically significant (P＜0.05).The auxiliary ventilation time in the observation group was shorter than that of the control group,and the difference was statistically significant (P＜0.05).The mortality of patients in the observation group was lower than that of the control group,and the difference was statistically significant (P＜0.05).Conclusion The effect of lung protective ventilation treating patients with severe chest trauma complicated with ARDS disease is remarkable.It can improve the blood gas analysis index and reduce the auxiliary ventilation time and mortality after ventilation.It has important clinical significance.

Key words： Pulmonary protective ventilation therapy Chest trauma Acute respiratory distress syndrome Clinical effect

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	LIANG Lei
	JIANG Wei

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LIANG Lei,JIANG Wei. Clinical effect of pulmonary protective ventilation in the treatment of severe chest trauma complicated with acute respiratory distress syndrome and its effect on ventilation function[J]. 中国当代医药, 2020, 27(5): 43-45转49.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I5/43

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