左炔诺孕酮宫内节育系统治疗妇科疾病的研究进展

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Abstract Levonorgestrel intrauterine contraceptive system (LNG-IUS),as a new type of intrauterine hormone contraceptive device imported from abroad,is a safe,effective and acceptable contraceptive method.LNG-IUS is released into uterine cavity at a dose of 20 μg Levonorgestrel (LNG) per day,which has comprehensive effects of thickening cervical mucus,preventing sperm from moving in uterine cavity and fallopian tube,inhibiting endometrial proliferation,etc.Like oral contraceptives,it has therapeutic effects other than contraception.LNG-IUS can effectively treat various gynecological diseases,including menorrhagia,hysteromyoma,endometriosis and adenomyosis with dysmenorrhea and endometrial hyperplasia.It can be used as an alternative to hysterectomy for women with bleeding problems,and can protect the endometrium in estrogen replacement therapy,and even has a certain alleviation effect on the early stage of endometrial cancer.This article aims to discuss the research progress of LNG-IUS in the treatment of gynecological diseases.

Key words： Levonorgestrel intrauterine system Uterine myoma Endometriosis Adenomyosis Endometrial hyperplasia

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	Articles by authors
	YI Ting-yan
	LI Jian-xia
	LUO Xue-mei

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YI Ting-yan,LI Jian-xia,LUO Xue-mei. Research progress of Levonorgestrel intrauterine contraceptive system for gynecological diseases[J]. 中国当代医药, 2020, 27(5): 16-18转33.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I5/16

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