氨溴索联合布地奈德雾化吸入治疗新生儿肺炎的临床效果

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Abstract Objective To investigate the clinical effect of Ambroxol combined with Budesonide atomized inhalation in the treatment of neonatal pneumonia.Methods Altogether 80 cases of neonatal children with pneumonia who were admitted to our hospital from December 2016 to November 2017 were selected as study subjects.According to the random number table method,the children were divided into the control group(40 cases)and the observation group(40 cases).All children were given routine treatment measures.The control group was given atomized inhalation of Ambroxol on the basis of the routine treatment,and the observation group was given Ambroxol combined with Budesonide atomized inhalation.The tidal breathing indexes(respiratory rate,tidal volume,peak time ratio,peak expiratory flow rate)before and after treatment were compared between the two groups,and the clinical symptom relief time (the disappearance time of the voice,lip purpura,cough and breath shortness),hospitalization time,treatment effect and adverse reactions were compared between the two groups.Results There were no significant differences in the tidal breathing indexes between the two groups before treatment(P＞0.05).The respiratory rate and peak expiratory flow rate of the two groups after treatment were lower than those before treatment,the tidal volume was more than that before treatment,peak time ratio and peak expiratory flow rate were higher than those before treatment,and the differences were statistically significant(P＜0.05).The respiratory rate and peak expiratory flow rate in the observation group after treatment were lower than those in the control group,the tidal volume was more than that in the control group,peak time ratio and peak expiratory flow rate were higher than those in the control group,and the differences were statistically significant(P＜0.05).The clinical symptom relief time and hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).The total effective rate of treatment in the observation group was 97.50%,which was significantly higher than that in the control group (80.00%),and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P＞0.05).Conclusion The combination of Ambroxol and Budesonide atomized inhalation can effectively improve the tidal breathing indexes of children,shorten the disappearance time of clinical symptoms,improve the therapeutic effect,and has a high clinical value,which is worthy of promotion.

Key words： Ambroxol Budesonide Atomized inhalation Neonatal pneumonia Therapeutic effect

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	ZOU Zhao-cheng

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ZOU Zhao-cheng. Clinical effect of Ambroxol combined with Budesonide atomized inhalation in the treatment of neonatal pneumonia[J]. 中国当代医药, 2019, 26(2): 131-133转136.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I2/131

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