血清PCT、CRP、WBC在脓毒症患者病情及预后评估中的应用价值

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Abstract Objective To explore the value of serum procalcitonin(PCT),C-reactive protein(CRP)and white blood cell count(WBC)in the evaluation of the condition and prognosis of sepsis patients.Methods One hundred and sixteen patients with sepsis admitted to our hospital from January 2016 to December 2017 were selected.Among them,they were further divided into sepsis group(n=77),severe sepsis group(n=21),and septic shock group(n=18).The serum levels of PCT,CRP,and WBC,band the survival status of the patients after 2 weeks of hospitalization and the corresponding indexes in the three groups were observed and compared.The correlations between serum PCT and CRP,and PCT and WBC were analyzed.Results The levels of PCT,CRP and WBC in the three groups were significantly different(P＜0.01）.As the severity of sepsis increased,the levels of PCT,CRP,and WBC increased significantly(P＜0.01）.After 2-week treatment,83 patients improved their conditions,25 cases were invalid,and 8 cases died.The PCT,CRP,and WBC levels in the death cases were significantly higher than those in the invalid and improved cases.The PCT,CRP,and WBC levels in invalid cases were significantly higher than those in the improved cases(P＜0.01）.The Pearson correlation analysis showed that serum CRP and WBC were both positively correlated with PCT (r＞0,P＜0.01）,and the correlation between CRP and PCT was greater than that between WBC and PCT.Conclusion Serum PCT,CRP and WBC levels are all closely related to the severity of sepsis.The higher the levels,the more severe the patient′s condition is,and the worse the prognosis is.The evaluation level of CRP and PCT is better than that of WBC.

Key words： Sepsis Procalcitonin C-reactive protein White blood cell count

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	Articles by authors
	XIE Shu-feng
	QI Ying-jing
	FENG Ming-tao
	ZENG Guan-yin

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XIE Shu-feng,QI Ying-jing,FENG Ming-tao, et al. Application value of serum PCT，CRP，WBC in assessing the condition and prognosis of patients with sepsis[J]. 中国当代医药, 2018, 25(26): 54-56.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I26/54

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