纤维支气管镜肺泡灌洗术对重症肺炎患者炎性因子及肺功能的影响

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Abstract ObjectiveTo investigate the effect of bronchofibroscopic bronchoalveolar lavage on inflammatory factor and lung function in patients with severe pneumonia.Methods80 patients with severe pneumonia treated in our hospital from February 2015 to December 2016 were selected as subjects,and they were divided into two groups by random number table method,40 cases in each group.Control group was given conventional treatment,while observation group was given bronchofibroscopic bronchoalveolar lavage based on control group.The inflammatory factors and lung function factors were compared between the two groups.ResultsBefore treatment,the STREM-1,HMGB-1,CD11b positive neutrophils,FVC,FEV1and FVC/FEV1were compared of patients between the two groups,and the differences were not statistically significant(P＞0.05).After treatment,the STREM-1,HMGB-1,CD11b positive neutrophils,FVC,FEV1and FVC/FEV1of patients in the two groups were significantly lower than before treatment,the STREM-1,HMGB-1 and CD11b positive neutrophils of patients in the observation group were lower than those in the control group,while the FVC,FEV1and FVC/FEV1in the observation group were higher than those in the control group,the differences were statistically significant(P＜0.05).ConclusionBronchofibroscopic bronchoalveolar lavage for patients with severe pneumonia is effective,it can improve lung function and reduce inflammatory response.

Key words： Severe pneumonia Bronchofibroscopic Bronchoalveolar lavage Lung function Inflammatory factor

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	Articles by authors
	YE Xian-qin
	XU Wei-zhen
	MO Jian-wei
	LIU Bin
	WU Chun-yan

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YE Xian-qin,XU Wei-zhen,MO Jian-wei, et al. Effect of bronchofibroscopic bronchoalveolar lavage on inflammatory factor and lung function in patients with severe pneumonia[J]. 中国当代医药, 2018, 25(2): 35-37.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I2/35

[1]	陈琼，凌文通，韩慧，等.重症肺炎患者BALF和血清IL-6、PCT水平变化及其意义研究[J].国际检验医学杂志，2016，37（21）：3053-3054.
[2]	石泽亚，秦月兰，祝益民，等.纤维支气管镜肺泡灌洗联合振动排痰治疗重症肺炎机械通气患者的效果观察：一项286例患者前瞻性随机对照研究[J].中华危重病急救医学，2017，29（1）：66-70.
[3]	陈亮，朱蓉，洪永青.纤维支气管镜在不间断机械通气重症肺炎诊治中的应用[J].临床肺科杂志，2017，22（4）：662-666.
[4]	杨兆辉，段瑞祥，杨晶，等.纤维支气管镜与肺泡灌洗术治疗老年重症肺部感染患者的疗效分析[J].中华医院感染学杂志，2016，26（6）：1300-1302.
[5]	陆再英，钟南山.《内科学》[M].第七版.北京：人民卫生出版社，2008，15-29.
[6]	倪楠，林琳.支气管肺泡灌洗治疗老年重症肺炎的临床疗效观察[J].中华老年多器官疾病杂志，2016，15（1）：34-37.
[7]	石泽亚，秦月兰，祝益民，等.振动排痰联合纤维支气管镜肺灌洗治疗重症肺炎机械通气患者的临床研究[J].中国内镜杂志，2016，22（10）：1-5.
[8]	金巍，徐靖华，刘建光，等.纤维支气管镜对急诊重症肺炎合并呼吸衰竭患者呼吸功能及血清炎症因子水平的影响[J].现代生物医学进展，2016，16（24）：4687-4689.
[9]	李斯南.肺泡灌洗对急诊重症肺炎合并呼吸衰竭患者血清学指标的影响[J].临床肺科杂志，2016，21（6）：1142-1144.
[10]	黄沛全，杨德茂，黄泽鸿.纤维支气管镜肺泡灌洗治疗对急诊重症肺炎合并呼吸衰竭患者血清学指标的影响[J].海南医学院学报，2015，21（7）：998-1001.
[11]	管彩虹，楼雅芳，陈旭燕.纤维支气管镜灌洗与常规治疗对重症肺部感染合并肺不张的疗效分析[J].中国内镜杂志，2014，20（6）：612-615.
[12]	黄有环，王瑞光，李志良.肺泡灌洗对急性重症肺炎合并呼吸衰竭患者的治疗效果[J].安徽医学，2017，38（4）：463-465.
[13]	彭川，韩文龙，邱渊.重症肺炎患者血清和肺泡灌洗液中IL-6和IL-10水平的变化及其与预后的相关性[J].海南医学，2016，27（18）：2956-2958.
[14]	刘胜华，温建立，邱蓓，等.重症肺炎患者血清及肺泡灌洗液中炎性因子水平及临床意义[J].中华医院感染学杂志，2016，26（24）：5587-5589.
[15]	刘晶.纤支镜灌洗治疗肺炎合并脓毒症的疗效分析[J].标记免疫分析与临床，2016，23（4）：410-412.
[16]	Sircar M，Ranjan P，Gupta R，et al.Impact of bronchoalveolar lavage multiplex polymerase chain reaction on microbiological yield and therapeutic decisions in severe pneumonia in intensive care unit[J].J Crit Care，2016，31（1）：227-232.