产妇行产前C反应蛋白及甲状腺功能检测的临床应用价值

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Abstract Objective To analyze and discuss the clinical application value of routine prenatal examination combined with C reaction protein(CRP)and thyroid function detection in parturients.Methods A total of 160 cases of parturients and who received prenatal examination in our hospital from December 2015 to May 2017 were randomly included into the discussion,and were received routine prenatal examination combined with CRP and thyroid function detection.And were grouped according to the results,which the simple CRP level abnormal group,the simple thyroid dysfunction group,abnormal combination of abnormal CRP and thyroid function of combined abnormal group,the control group with two normal indexes,40 cases in each group.Then,the status of parturients and foetuses between each group were compared and analyzed.ResultsThe condition of two groups of newborns were compared,including stillbirth,asphyxia of the newborn,malformation of the newborn and so on.And the incidence of combined abnormal group was 20.00%,which was higher than that in the simple CRP group of 15.00%,simple thyroid dysfunction abnormal group of 8.00%and control group of 1.25%,respectively,and the difference was statistically significant(P＜0.05）.The simple CRP abnormal group was 15.00%.which was higher than that the simple thyroid dysfunction group of 8.00%and the control group of 1.25%,the difference was statistically significant(P＜0.05）.The simple thyroid dysfunction group was 8.00%,which was higher than that in the control group of 1.25%,and the difference was statistically significant(P＜0.05）.Conclusion It is suggested that the parturient should receive CRP and thyroid function detection when receiving routine prenatal examination,which in order to find out whether the pregnant women have the high risk pregnancy factors in time,and it is beneficial effect on the adoption of corresponding interventions,and to further ensure the safety of mother and child.

Key words： Parturients Antenatal examination Project CRP and thyroid function detection

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	LIANG Jie-ying

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LIANG Jie-ying. Clinical application value of prenatal C reaction protein and thyroid function detection[J]. 中国当代医药, 2018, 25(21): 133-136.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I21/133

[1]	顾维正.甲状腺疾病与妊娠[J].中国医师进修杂志，2003，26（11）：251-253.
[2]	余芳，薛耀明，李晨钟，等.血清 IL-6、hs-CRP 与妊娠期糖尿病胰岛素抵抗的关系[J].南方医科大学学报，2007，27（6）：799-801.
[3]	王秀梅.妊娠期糖尿病高危孕妇甲状腺功能及甲状腺自身抗体变化的研究[J].中国医药导报，2011，8（20）：20-21.
[4]	汪小娟，马志海，林晓华，等.妊娠糖尿病孕妇糖化血红蛋白与甲状腺激素水平分析[J].河北医学，2012，18（8）：1060-1063.
[5]	康苏娅，汪云，伍理.妊娠期糖尿病孕妇甲状腺功能及妊娠结局的研究[J].现代妇产科进展，2014，23（1）：50-52.
[6]	吴素萍.妊娠期甲状腺功能减退症与妊娠期高血压的关系研究[J].实用心脑肺血管病杂志，2013，21（7）：77-78.
[7]	杨东群，崔建玲.妊娠期高血压疾病孕妇妊娠晚期甲状腺功能异常的状况分析[J].中国妇幼保健，2016，31（1）：43-45.
[8]	Pradhan AD，Manson JE，Rifai N，et al.C-Reactive Protein，Interleukin 6，and Risk of Developing Type 2 Diabetes Mellitus[J].JAMA，2001，286（3）：327-334.
[9]	Barzilay JI，Abraham L，Heckbert SR，et al.The relation of markers of inflammation to the development of glucose disorders in the elderly：the cardiovascular health study[J].Diabetes，2001，50（10）：2384-2389.
[10]	Sacks GP，Seyani L，Lavery S，et al.Maternal C-reactive protein levels are raised at 4 weeks gestation[J].Hum Reprod，2004，19（4）：1025-1030.
[11]	Qiu C，Luthy DA，Zhang C，et al.A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsia[J].Am J Hypertens，2004，17（2）：154-160.
[12]	Wolf M，Sauk J，Shah A，et al.Inflammation and glucose intolerance：a prospective study of gestational diabetes mellitus[J].Diabetes Care，2004，27（1）：21-27.
[13]	刘陶，刘晴，杨冬，等.早孕期血清脂联素、瘦素、肿瘤坏死因子α、C反应蛋白水平与胰岛素抵抗的相关性[J].中华医学杂志，2011，91（15）：1058-1060.
[14]	Smirnakis KV，Plati A，Wolf M，et al.Predicting gestational diabetes：choosing the optimal early serum marker[J].Am J Obste Gynecol，2007，196（4）：410.e1-6.
[15]	Berggren EK，Roeder HA，Boggess KA，et al.First-trimester maternal serum C-reactive protein as a predictor of thirdtrimester impaired glucose tolerance[J].Reprod Sci，2015，22（1）：90-93.
[16]	田明，吴连方.妊娠期糖尿病孕妇并发妊娠期高血压疾病的临床特点及血清CRP、IL-6、TNF-α的水平分析[J].中国妇幼保健，2012，27（9）：1318-1321.