乳腺癌新辅助化疗后前哨淋巴结活检的可行性研究

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Abstract Objective To investigate the predictive value of sentinel lymph node biopsy （SLNB）for axillary lymph node staging after neoadjuvant chemotherapy （NAC）.Methods Thirty-one new breast cancer patients admitted to our hospital from January 2017 to March 2018 were selected as the research objects,and were divided into control group（16 cases）and experimental group（15 cases） by random number table method.After NAC,SLNB was performed in the experimental group,followed by modified radical mastectomy plus axillary lymph node dissection.The control group underwent NAC after SLNB,followed by modified radical mastectomy plus axillary lymph node dissection.The detection rate,false negative rate,accuracy,negative sensitivity and sentinel lymph node metastasis rate of the two groups were compared through the pathological conditions of the detected lymph nodes.Results There was no statistically significant difference in false negative rate,accuracy and negative sensitivity between the two types of patients(P>0.05).The detection rate of sentinel lymph node metastasis in the experimental group was lower than that in the control group,and the difference was statistically significant (P ＜0.05）.Conclusion Sentinel lymph node biopsy after neoadjuvant chemotherapy can also predict axillary lymph node metastasis,but further study is needed for long-term prognosis.

Key words： Breast neoplasms Sentinel lymph node biopsy Neoadjuvant chemotherapy Modified radical mastectomy Axillary lymph node dissection

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	Articles by authors
	LI Min
	HUANG Zhan
	LI Xiao-yong
	LEI Rui-wen
	YANG Chuan-sheng
	ZHANG Kai
	CHEN Zhuo-rong
	LU Hai

Cite this article:

LI Min,HUANG Zhan,LI Xiao-yong, et al. Feasibility of sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer[J]. 中国当代医药, 2018, 25(20): 63-65.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I20/63

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