药学服务对系统性红斑狼疮患者服药依从性及病情控制的影响

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Abstract ObjectiveTo understand the effects of pharmacological services on medication compliance and sickness condition control of patientswith systemic lupus erythematosus(SLE).MethodsA total of 70 SLE patients confirmed by department of rheumatology and immunology in our hospital from January 2016 to April 2017 were selected as subjects.They were randomly divided into two groups,each with 35 cases.The control group was given regular pharmaceutical services,and the intervention group was given targeted pharmaceutical services.The Morisky medication compliance scale(MMAS-8)and the disease activity in SLE scale(SLE-DAI)were compared between the two groups before and 2,4,6 months after intervention.ResultsBefore intervention,there was no significant difference in MMAS-8 and SLEDAIscores between the two groups　(P＞0.05).In the 2,4,6 months after the intervention,the MMAS-8 scores of the patients in the intervention group were higher than those in the control group,and the differenceswere statistically significant(P＜0.05).In the 2,4,6 months after the intervention,the SLE-DAI scores of the patients in the intervention group were lower than those in the control group,and the differenceswere statistically significant(P＜0.05).ConclusionPharmacological services for patients with SLE can improve the compliance ofmedication compliance.Good adherence to medication is beneficial to the sickness condition control of patientswith SLE.And it has great significance to the longterm prognosis of patientswith SLE.It isworth spreading.

Key words： Systemic lupus erythematosus Pharmacological services Disease activity Medication compliance

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FU Shi-jing. Effect of pharmacological services on medication com p liance and sickness condition control of patientsw ith system ic lupus erythematosus[J]. 中国当代医药, 2018, 25(16): 168-170.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I16/168

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