呼出气一氧化氮测定在哮喘-慢性阻塞性肺疾病重叠综合征的临床应用

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Abstract ObjectiveTo study the clinical application effect of exhaled nitric oxide measurement on asthama-chronic obstructive pulmonary disease　(ACOS).MethodsForty-two patients with asthma-chronic,simple asthma,simple chronic obstructive pulmonary disease and non-respiratory diseases who were admitted and diagnosed in our hospital from July 2013 to March 2017 were selected and observation group,control group A,control group B and control group C respectively.before medication,four groups of patients accepted the measurement of exhaled nitric oxide,and the differences between the measurement of exhaled nitric oxide in observation group and the control group were compared.ResultsThe feNO value of the patients in the observation group was lower than that of the control group A,and the difference was statistically significant(P<0.05).FeNO values of patients in the observation group were significantly higher than those in the control groups B and C,and the differences were statistically significant(P<0.05).The probability of FeNO≥27 ppb in the observation group was higher than that in the control group A,and there was no significant difference(P<0.05).The probability of FeNO≥27 ppb in the observation group was significantly higher than that in the control group B and C,and the differences were statistically significant(P<0.05).ConclusionThe measured value of exhaled nitric oxide in patients with asthma-chronic obstructive pulmonary disease is significantly different from those of asthma alone,COPD alone,and other non-respiratory diseases.Therefore,exhaled nitric oxide measurement plays a great differential diagnosis role in asthma-chronic obstructive pulmonary disease and has an application value.

Key words： Exhaled nitric oxide Chronic obstructive pulmonary disease（COPD） Asthma Asthma-chronic obstructive pulmonary disease

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	Articles by authors
	DING Yue-mei
	SHI Chang-li
	YU Jiang-qing
	WANG Qing-feng

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DING Yue-mei,SHI Chang-li,YU Jiang-qing, et al. Clinical app lication of exhaled nitric oxide measurement in asthamachronic obstructive pulmonary disease[J]. 中国当代医药, 2018, 25(17): 33-35.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I17/33

[2]	成芳娟，牟向东，关键，等.呼出气一氧化氮在哮喘-慢阻肺重叠综合征诊断中的价值[J].农垦医学，2017，39（4）：298-301.
[1]	Feng JX，Lin Y，Lin J，et al.Relationship between Fractional Exhaled Nitric Oxide Level and Efficacy of Inhaled Corticosteroid in Asthma-COPD Overlap Syndrome Patients with Different Disease Severity[J]J Korean Med Sci，2017，32（3）：439-447.
[3]	刘凌云.哮喘－慢阻肺重叠综合征患者呼出气一氧化氮与诱导痰嗜酸粒细胞及肺功能的相关性研究[J].岭南急诊医学杂志，2016，21（3）：226-227，232.
[4]	吉泽，潘星，姬峰，等.呼出气一氧化氮检测在哮喘-慢阻肺重叠综合征治疗中的应用价值[J].第二军医大学学报，2016，37（10）：1250-1255.
[5]	吴宇晗，陈宏.辅助诊断哮喘-慢阻肺重叠综合征的炎性标志物的研究进展[J].实用心脑肺血管病杂志，2017，25（7）：10-12.
[6]	谢晓然，张智勇，李爽，等.FeNO检测与ACOS病情活动的相关性分析[J].微量元素与健康研究，2017，34（3）：91，94.
[7]	吴孟烽，许曼，韦冬琴，等.糖皮质激素联合噻托溴铵治疗哮喘-慢阻肺重叠综合征的临床研究[J].内科，2016，11（6）：910-911.
[8]	Barrecheguren M，Esquinas C，Miravitlles M.Cómo podemos identificar a los pacientes con fenotipo mixto asma-EPOC（ACOS）en la práctica clínica?[J].Archivos De Bronconeumologia，2016，52（2）：59-60.
[9]	贺岚，付秀华.哮喘-慢阻肺重叠综合征患者240例临床特征分析[J].中国社区医师，2016，32（34）：15-16.
[10]	韩美荣，陈燕，李剑平.肺功能测定鉴别支气管哮喘、慢阻肺及哮喘慢阻肺重叠综合征的临床意义[J].临床肺科杂志，2016，21（5）：934-937.
[11]	张树荣，安忠碧，张彦，等.呼出气一氧化氮在老年哮喘-慢阻肺重叠综合征患者中的测定[J].临床肺科杂志，2016，21（2）：217-219.
[12]	邓玎玎，周爱媛，双庆翠，等.呼出气一氧化氮测定对支气管哮喘-慢性阻塞性肺疾病重叠综合征的诊断价值[J].中华结核和呼吸杂志，2017，40（2）：98-101.
[13]	杜丽艳，庞桂芬，姜锋.呼出气一氧化氮在哮喘-慢阻肺重叠综合征中的应用[J].承德医学院学报，2017，34（3）：241-244.
[14]	Goto T，Camargo CA Jr，Hasegawa K.Fractional exhaled nitric oxide levels in asthma-COPD overlap syndrome：analysis of the National Health and Nutrition Examination Survey，2007～2012[J].Int J Chron Obstruct Pulmon Dis，2016，11（1）：2149-2155.
[15]	韩国敬，许菡苡，胡红，等.哮喘-慢阻肺重叠综合征、哮喘及慢阻肺患者的肺功能及临床特征比较[J].解放军医学院学报，2016，37（11）：1122-1125，1189.