他汀类强化降脂治疗对行PCI术双心病患者焦虑、抑郁状态的影响研究

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Abstract Objective To study the influence of statins intensive lipid-lowering therapy on anxiety and depression of patients with coronary heart disease and psychological disease undergoing PCI.Methods A total of 63 patients with coronary heart disease undergoing PCI with anxiety and depression treated in our hospital from January 2014 to January 2017 were selected as subjects.The level of anxiety and depression,the SAS and SDS scores were compared before and after patients were treated with statins intensive lipid-lowering therapy for eight weeks.Results The patients after statins intensive lipid-lowering therapy were less anxious than before treatment,and the SAS score was higher than before treatment,and the differences were statistically significant(P＜0.05).The degree of depression and SDS score were compared before and after statins intensive lipid-lowering therapy,and the differences were not statistically significant(P＞0.05).Conclusion Statins intensive lipid-lowering therapy may worsen the anxiety condition of patients with heart disease and psychological disease undergoing PCI.For such patients,the statins intensive lipid-lowering therapy should be carried out carefully,and it would be more appropriate to use statins with small dose or moderate intensity to investigate the influence on anxiety and depression.

Key words： Statins Anxiety Depression Intensive lipid-lowering Coronary heart disease and psychological disease

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	ZHANG Wen-ying
	XIE Li
	ZHENG Yan-lin2

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ZHANG Wen-ying,XIE Li,ZHENG Yan-lin2. Influence of statins intensive lipid-lowering therapy on anxiety and depression of patients with coronary heart disease and psychological disease undergoing PCI[J]. 中国当代医药, 2018, 25(11): 114-116转120.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I11/114

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