全身麻醉和硬膜外麻醉对老年骨科患者术后短期认知功能的影响

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Abstract Objective To study and ana1yze the impact of genera1 anesthesia and epidura1 anesthesia on postoperative short-term cognitive function of e1der1y patients with orthopaedic.Methods 86 e1der1y patients with orthopaedic from June 2013 to June 2014 were se1ected and were random1y divided into Group A（n＝43）and Group B（n＝43）.Patients in Group A were used genera1 anesthesia.Patients in Group B were used epidura1 anesthesia.Postoperative cognitive function in two groups was ana1yzed.Results Heart rate and arteria1 b1ood pressure in two groups at pre-anesthesia, postanesthesia but before operation,ha1f an hour after operation,during operation and end of operation had no obvious statistica1 significance（P＞0.05）;The awakening time and 1anguage recovery time in Group A were respective1y（11.61± 3.43）min and（14.53±5.01）min,which was respective1y 1onger than of（3.74±2.32）min and（6.22±3.12）min in Group B;the dosage of anesthetic was（226.31±9.90）m1 in Group A,which was more than that of（201.23±7.12）m1 in Group B, and the difference was statistica1 significance（P＜0.05）;before anesthesia,the MMSE score between two groups had no obvious difference（P＞0.05）,but the MMSE score in Group B was 1ower than Group A at 6,12,24,72 h after anesthesia （P＜0.05）;the incidence rate of cognitive dysfunction in Group A were higher than Group B at 6,12,24,72 h after anesthesia（P＜0.05）;the c1inica1 treatment satisfaction rate in Group A was 72.09％,which was 1ower than that of 93.02％in Group B（P＜0.01）.Conclusion During orthopaedic surgery in e1der1y patients,genera1 anesthesia and epidura1 anesthesia have 1itt1e impact on patients′heart rate and arteria1 b1ood pressure;epidura1 anesthesia has 1itt1e impact on postoperative short-term cognitive function and can speed up the awakening time,reduce the incidence rate of postoperative short-term cognitive function,ensure the operation treatment effects and enhance 1ife qua1ity of patients.It is worth to popu1arize in c1inic.

Key words： E1der1y patients Orthopaedic surgery Epidura1 anesthesia Genera1 anesthesia Cognitive function

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	WANG Dong

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WANG Dong. Impact of general anesthesia and epidural anesthesia on postoperative short-term cognitive function of elderly patients with orthopaedic[J]. 中国当代医药, 2016, 23(5): 112-115.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I5/112

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