选择性肝动脉化疗栓塞术联合经皮微波消融治疗大肝癌的临床观察

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Abstract Objective To explore the effect of selective hepatic artery chemoembolization combined with percutaneous microwave coagulation therapy（PMCT）in the treatment of large hepatocarcinoma. Methods 56 patients with large hepatocarcinoma in our hospital from June 2011 to June 2014 were selected and divided into the observation group（30 patients）and the control group（26 patients）according to the wishes of patients and their families.The observation group was treated with TACE combined with PMCT，the control group was treated with TACE.The blood indicator before and after treatment，the short-term efficacy and the long-term survival rate in the two groups was compared. Results The level of AFP in the observation group after operation was lower than that before operation and in the control group after operation，with significant difference（P＜0.01）.The maximum diameter of the tumor in the observation group after operation was less than that before operation and in the control group after operation，with significant difference（P＜0.05）.The recent clinical effective rate of the observation group was 86.7%，which was higher than that of the control group 57.7%，with significant difference（P＜0.01）.The survival rate of the observation group in 6，12 and 18 months was higher than that of the control group，with significant difference（P＜0.05）.The adverse reactions of the two groups were slightly，after conservative treatment，all returned to normal. Conclusion TACE combined with PMCT can improve the short-term efficacy and long-term survival rate of patients with large hepatocarcinoma，and the safety is good，it is worthy of clinical promotion and application.

Key words： Large hepatocarcinoma Chemoembolization Percutaneous microwave coagulation therapy

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	ZENG Li
	HE Yong-yue
	WANG Dao-du
	LIN Qiao-luan

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ZENG Li,HE Yong-yue,WANG Dao-du, et al. Clinical observation of selective hePatic artery chemoembolization combined with Percutaneous microwave coagulation theraPy in the treatment of large hePatocarcinoma[J]. 中国当代医药, 2016, 23(11): 42-44转47.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I11/42

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