左炔诺孕酮宫内节育系统和安宫黄体酮在围绝经期异常子宫出血治疗中的疗效观察

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Abstract Objective To exp1ore the curative effect of 1evonorgestre1 intrauterine system and medroxyprogesterone acetate in the treatment of abnorma1 uterine b1eeding in the perimenopausa1 period.Methods 115 cases of abnorma1 uterine b1eeding in the perimenopausa1 period from January 2013 to January 2015 in our hospita1 were se1ected and divided into the contro1 group（55 cases）and the detection group（60 cases）according to different treatment methods.The contro1 group was treated with estradio1 va1erate and medroxyprogesterone acetate，the observation group was treated with 1evonorgestre1 intrauterine system and medroxyprogesterone acetate.The endometria1 thickness，menstrua1 b1ood vo1-ume，the 1eve1 of hemog1obin and the contro1 b1eeding time，b1eeding comp1ete1y time，the c1inica1 curative effect in the two groups was compared.Results The endometria1 thickness after treatment in the two groups was 1ess than that before treatment，menstrua1 b1ood vo1ume after treatment in the two groups was 1ess than that before treatment，the 1eve1 of hemog1obin in the two groups was higher than that before treatment，with significant difference（P＜0.05）.The endometria1 thickness after treatment in the observation group was 1ess than that in the contro1 group after treatment，menstrua1 b1ood vo1ume after treatment in the observation group was 1ess than that in the contro1 group after treatment，the 1eve1 of hemog1obin after treatment in the observation group was higher than that in the contro1 group after treatment，with significant difference　（P＜0.05）.The contro1 b1eeding time，b1eeding comp1ete1y time in the observation group was shorter than that in the contro1 group，with significant difference　（P＜0.05）.The tota1 effective rate in the observation group was 98.3%，which was higher than 85.5%in the contro1 group，with significant difference（P＜0.05）.Conclusion The effect of 1evonorgestre1 intrauterine system and medroxyprogesterone acetate in the treatment of abnorma1 uterine b1eeding in the perimenopausa1 period is significant，it is worthy of c1inica1 promotion and app1ication.

Key words： Levonorgestre1 intrauterine system Medroxyprogesterone acetate Perimenopausa1 period Abnorma1 uterine b1eeding

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	HAN Jin-xiu

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HAN Jin-xiu. Curative effect observation of levonorgestrel intrauterine system and medroxyprogesterone acetate in the treatment of abnormal uterine bleed-ing in the perimenopausal period[J]. 中国当代医药, 2016, 23(14): 60-62.

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