呋喃西林联合康复新液治疗重症口腔溃疡的临床效果

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Abstract Objective To investigate the clinical efficacy of nitrofurazone combined with Kangfuxin in patients with severe mouth ulcers.Methods 90 patients of severe mouth ulcers treated from January 2006 to December 2015 in our department were selected，the patients were divided into two groups by random digits table，with 45 cases in each group. The control group was only given nitrofurazone mouthwash，the treatment group were treated combined with Kangfuxin on the basis of control group.The efficacy and the content of secretory immunoglobulin A（sIgA）and immunoglobulin G （IgG）were compared between two groups before and after treatment.Results The symptoms were significantly improved in the treatment group，the effective rate and the total effective rate in treatment group was 28.89%，91.11%respectively，with15.56%and 80.00%respectively in control group，the ulcer healing time in the treatment group was significantly shorter than that in the control group［（3.2±0.5）d vs（4.9±1.3）d］，there were statistically significant difference between two groups（P＜0.05）.The content of saliva sIgA in the treatment group after treatment 7 d was significantly higher than that in control group［（65.7±10.5）g/L vs（52.0±9.4）g/L］，and the content of IgG was significantly lower than that in the control group　［（23.5±5.5）g/L vs（35.3±7.5）g/L］，there was statistically significant difference between two groups　（P＜0.05）.Conclusion Nitrofurazone combined with Kangfuxin in treatment of patients with severe mouth ulcers has a good clinical efficacy，high security，can reduce patients′suffering and improvie patients′satisfaction and quality of care，it can be used widely in clinic.

Key words： Severe mouth ulcers Nitrofurazone Kangfuxin

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	Articles by authors
	LIN Wei
	GE Ying
	FENG Wei-ping

Cite this article:

LIN Wei,GE Ying,　FENG Wei-ping. Clinical application of nitrofurazone combined with Kangfuxin in patients with severe mouth ulcers[J]. 中国当代医药, 2016, 23(17): 101-103.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I17/101

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