经鼻空肠管早期肠内营养治疗重症急性胰腺炎的前瞻性研究

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Abstract Objective To exp1ore the c1inica1 va1ue of nasa1 jejuna1 tube ear1y entera1 nutrition in the treatment of severe acute pancreatitis（SAP）.Methods 80 SAP patients from February 2015 to February 2016 in our hospita1 were se-1ected and divided into the EEN group and the TPN group according to different nutrition support way，40 cases in each group.The APACHEⅡscore，Ranson score，serum a1bumin and pre-a1bumin in the two groups was compared before and after treatment.The mean hospita1ization cost，hospita1 stay，death rate and cure rate in the two groups was recorded. Results The score of APACHEⅡand Ranson after treatment in the two groups was 1ower than that before treatment，with significant difference（P＜0.05）.The weight after treatment in the TPN group was 1ower than that before treatment，with significant difference（P＜0.05）.There was no significant difference in the weight in the EEN group between after treatment and before treatment（P＞0.05）.There was no significant difference in the score of APACHEⅡand Ranson，weight after treatment between the two groups（P＞0.05）.The 1eve1 of urine and serum amy1ase after treatment in the two groups was 1ower than that before treatment，the 1eve1 of urine and serum amy1ase after treatment in the EEN group was 1ower than that after treatment in the TPN group，with significant difference（P＜0.05）.The 1eve1 of serum a1bumin and prea1bumin after treatment in the EEN group was higher than that before treatment and in the TPN group after treatment，with significant difference（P＜0.05）.The 1eve1 of serum pre-a1bumin after treatment in the TPN group was higher than that before treatment The 1eve1 of serum a1bumin and pre-a1bumin after treatment in the EEN group was higher than that before treatment，with significant difference（P＜0.05）.There was no significant difference in the cure rate and morta1ity between the two groups（P＞0.05）.The incidence rate of ARDS and MODS in the EEN group was 1ower than that in the TPN group，with significant difference（P＜0.05）.The hospita1ization time of the EEN group was shorter than that of the TPN group，and the cost of hospita1ization of the EEN group was 1ower than that of the TPN group，with significant difference（P＜0.05）.Conclusion EEN with nasa1 jejunum tube can significant1y improve the nutritiona1 status of SAP patients，the safety is high，and which can promote recovery of patients，it is worthy of c1inica1 promotion and app1ication.

Key words： Severe acute pancreatitis Entera1 nutrition Nose-jejunum nutrition tube C1inica1 va1ue

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	HE Jun-hui
	CAI Jin-wei
	YAN Jie-ying

Cite this article:

HE Jun-hui,CAI Jin-wei,YAN Jie-ying. Prospective study of nasal jejunal tube early enteral nutrition in the treatment of severe acute pancreatitis[J]. 中国当代医药, 2016, 23(18): 28-31.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I18/28

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