颅脑损伤伴发颅内感染患者的临床特点和急性预后的相关因素分析

Abstract
Figure/Table
References (14)
Related Citation (15)

Download: PDF (0 KB) HTML (38 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical characteristics and factors of acute prognosis in traumatic brain injury patientswith intracranial infection.M ethods The clinical data of 245 patientswith traumatic brain injury in our hospital from April 2013 to October 2015 were employed and retrospectively analyzed.The clinicalmanifestations in intracranial infection patients were collected，and analyzed with chi square test of single factor analysis to find the risk factors of intracranial infection，in which，the significant ones were deal with logistic regression analysis.Results Among of the 245 patients，42 cases（17.1%）occurred with intracranial infection，in which clinical features for persistent head of pain were 37 cases（88.1%），headache with vomiting were 30 cases（71.4%），irregular fever were 35 cases（83.3%），.Clinical characteristics included obviousmeningeal irritation and nerve injury of optic nerve，oculomotor nerve，auditory nerve.Operative time，preoperative GCSscore less than 8 points，open craniocerebral injury，surgical site on the screen，drainage tube indwelling timemore than 7 days，leakage of cerebrospinal，diabetesmellitus etc.were for risk factors of intracranial infection related，in which，leakage of cerebrospinal fluid could bring the highest risk（OR value=7.17）.Therewas no significant relationship between sex，age，preoperative use of antibiotics and the occurrence of intracranial infection（P＞0.05）.Conclusion Prevented the intracranial infection according to the risk factors in the early stage.Paid close attention to the clinicalmanifestations of patients，to detect the patientswith intracranial infection and given treatment as early.

Key words： Craniocerebral injury Intracranial infection Risk factors

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LIJian-hua
	WU Yi-yi
	REN Zhen-chao

Cite this article:

LIJian-hua,WU Yi-yi,REN Zhen-chao. Analysis on clinical characteristics and acute prognosis of patients w ith craniocerebral injury com p licated w ith intracranial infection[J]. 中国当代医药, 2016, 23(21): 54-56转59.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I21/54

［9］	卢林友，黄英文，张国庆.颅脑损伤患者脑积水分流术后感染病原菌分布与耐药性监测［J］.中华医院感染学杂志，2015，25（17）：3890-3892.
［10］	王浩，吕建华，田力学.257例颅脑损伤患者合并肺部感染的特点及防治［J］.中华医院感染学杂志，2014，24（6）：118-119.
［1］	曹艳华，黄李平.影响恢复期颅脑损伤患者预后的相关因素分析［J］.当代医学，2013，19（30）：24-25.
［8］	朱司泉，王增亮，徐丹书，等.重型颅脑损伤去骨瓣减压术后颅内感染的诊疗研究［J］.中华医院感染学杂志，2014，24（2）：441-443.
［1］	Conen A，Walti LA，Fluckiger U，et a l.Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults：a retrospective analysis over an 11-year period［J］.Clin Infect Dis，2008，47（1）：73-82.
［2］	HallWA.Postoperative central nervous system infection：incidence and associated factors in 2111 neurosurgical procedures［J］.Clin Infect Dis，2007，45（1）：55-59.
［3］	Alexander M.Levels of vancomycin in the cerebral interstitial fluid after severe head injury［J］.Intens Care Med，2015，32（2）：325-328.
［4］	孙鹏，李双成，陈凌志.重型颅脑损伤患者术后不同营养方式对颅内感染影响的研究［J］.中华医院感染学杂志，2014，24（1）：173-175.
［5］	陈素娇，包红霞，李亚丰.重症颅脑损伤并发肺部感染原因分析及早期物理治疗效果观察［J］.中华医院感染学杂志，2013，23（11）：2622-2624.
［6］	帅晖，田坤，李岩.重型颅脑损伤继发颅内感染的临床分析［J］.中华医院感染学杂志，2014，24（15）：3794-3795，3798.
［7］	陈春林，康晓明，陈力行，等.重型颅脑损伤开颅术后早期气管切开对防治肺部感染的作用研究［J］.实用心脑肺血管杂志，2014，19（7）：1120-1121.
［12］	舒宇峰，吴陈英，钟玉平，等.重症颅脑损伤患者肺部感染病原菌分布［J］.中华医院感染学杂志，2014，24（24）：6158-6159.
［13］	魏俊，何贵山，董伟，等.老年重型颅脑损伤63例救治分析［J］.中国误诊学杂志，2013，11（27）：6710-6711.
［14］	Aken MOV，Feelders RA，Marie SD，et al.Cerebrospinal fluid leakage during transsphenoidal surgery：postoperative external lumbar drainage reduces the risk formeningitis［J］. Pituitary，2014，7（7）：89-93.