|
|
|
| Clinical effect observation on the treatment of hand foot and mouth disease with the combination of the Shufeng Jiedu Capsules and Ribavirin |
| ZHANG Wen-zhong |
| Department of Pediatrics,the Sixth People′s Hospital of Zhengzhou City in Henan Province,Zhengzhou450005,China |
|
|
|
|
Abstract Objective To investigate the clinical effect of the treatment of children with hand foot and mouth disease by the combination of ShuFeng Jiedu Capsules and Ribavirin.Methods 60 patients from December 2014 to December 2015 in our hospital with pediatric clinical diagnosis of hand,foot and mouth disease in children with of general type were selected,according to the random number method,were randomly divided into two groups.The conventional treatment group(the control group)was treated with Ribavirin Injection,and the treatment group(observation group)was treated with Ribavirin combined with Shufeng Jiedu Capsules after treatment 5 days,and the patients were followed up for 3 days after the treatment.The children with rash subsided,oral herpes subsided time and cooling time of two groups were compared.Results After the treatment,the rash subsided time of observation group was(2.52±0.26)days,the control group was(4.01±0.57)days,the observation group was significantly shorter than that of control group,the difference was significant(P<0.05);the blebsubsidise time of observation group was(2.31±0.31)days,the control group was(3.46±0.57) days,the observation group was significantly shorter than that of control group,the difference was significant(P<0.05);after treatment,the observation group body temperature was(36.8±0.5)℃,the control group was(37.5±0.5)℃,the difference was significant(P<0.05);the cooling time of observation group was(2.2±1.1)days,the control group was(4.3±1.4)days, the observation group was significantly shorter than that of control group,the difference was significant(P<0.05).Conclusion Shufeng Jiedu Capsules combined with Ribavirin has better clinical efficacy in the treatment of children with hand foot and mouth disease,it is worthy of promotion.
|
|
|
|
|
|
| [1] |
孙莲，孟雅婧.玉屏风联合利巴韦林治疗小儿手足口病轻症疗效观察[J].中国临床医生，2014，42（8）：75-76．
|
| [2] |
王玉珍，庞保东．醒脑静注射液结合常规疗法治疗手足口病合并脑炎55例[J].上海中医药杂志，2015，47（12）：50-51．
|
| [3] |
罗玉慧.热毒宁注射液治疗手足口病临床疗效分析[J].临床医学，2014，32（12）：88-89．
|
| [4] |
卫生部.手足口病诊疗指南（2010）年版[J].国际呼吸杂志，2010，30（12）：1473.
|
| [5] |
王雪峰.手足口病的中医药预防与治疗[J].中国实用儿科杂志，2014，27（4）：421-423．
|
| [6] |
刘玉玲，何慧珍.中医论证清热利咽剂在手足口病中的应用[J].四川中医，2014，32（10）：31-32．
|
| [7] |
林丹薇，周琳，刘嘉萍，等.银翘清毒方治疗普通型手足口病60例临床观察[J].新中医，2014，46（12）：108-110．
|
| [8] |
孙浩武，张胜伟.加味升降散治疗手足口病合并脑干脑炎1例[J].河南中医，2014，34（10）：1940．
|
| [9] |
黄晓利，刘昕.甘露消毒丹加减联合透疹外洗方治疗普通型手足口病肺脾湿热证120例疗效观察[J].中医儿科杂志，2012，8（6）：36-38．
|
| [10] |
王书臣，罗海丽.疏风解毒胶囊治疗上呼吸道感染480例临床观察[J].世界中西医结合杂志，2014，4（12）：872-875．
|
| [11] |
刘颖，崔晓兰，时瀚，等.疏风解毒胶囊防治流感体内药效学实验研究[J].世界中西医结合杂志，2015，5（1）：35-36．
|
| [12] |
张春兰，刘凤英.疏风解毒胶囊联合西药治疗小儿手足口病134例疗效观察[J].山东中医杂志，2013，15（6）：539-540.
|
| [13] |
张俊，李蒙，刘雨欣，等.疏风解毒胶囊治疗流行性感冒86例临床观察[J].中药新药与临床药理，2015，21（5）：314-317.
|
| [14] |
张新娜，朱雯雯，孙俪，等.疏风解毒胶囊外泡内服治疗肠道病毒71型小儿手足口病疗效观察[J].中国中医急症，2016，24（8）：24-26.
|
| [15] |
刘刚，张军，孙翠英，等.疏风解毒胶囊与蓝芩口服液治疗小儿手足口病疗效比较[J].福建中医药，2015，19（8）：35-37.
|
| [16] |
罗海英，张欣俊.疏风解毒胶囊治疗手足口病109例临床疗效观察[J].辽宁中医药大学学报，2014，24（12）：82-85．
|
| [17] |
崔世兰，李明瀚，张颖.疏风解毒胶囊防治流感临床观察[J].实用中医内科，2015，19（11）：135-136．
|
| [18] |
陈炳泽.疏风解毒胶囊治疗小儿手足口病56例疗效观察[J].中国中西医结合儿科学，2013，15（6）：539-540.
|
| [19] |
邱欢，李振兴，朱童娜，等.疏风解毒胶囊体内抗病毒作用的实验研究[J].中药新药与临床药理，2014，25（1）：14-17.
|
| [20] |
吕伟伟，朱童娜，邱欢，等.疏风解毒胶囊抗病毒及抗菌的体外药效学实验研究[J].中药新药与临床药理，2013，24（3）：234-238.
|
| [21] |
何子龙，方文娟，张方博，等.疏风解毒胶囊肠吸收液对LPS诱导巨噬细胞释放细胞因子的影响[J].中国现代中药，2015，17（4）：345-348.
|
|
|
|
