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Effect observation of Chemical Peel combined with Adapalene Gel for external use treating mild to moderate acne |
LU Fu-qiong YU Zhen YANG Fan |
Prevention and Treatment Center of Chronic Disease in Shenzhen City of Guangdong Province,Shenzhen 518020,China |
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Abstract ObjectiveTo investigate the clinical effect of Chemical Peel combined with Adapalene Gel for external use treating mild to moderate acne.Methods200 patients with mild to moderate acne treated by our hospital from May 2015 to May 2016 were selected as object.They were randomly divided into two groups,and each grroup had 100 cases. The observation group was treated by Chemical Peel combined with Adapalene Gel for external use,while the control group was treated by simple Adapalene Gel.Treatment effect between two groups was compared.ResultsThe total effective rate in patients of the observation group(97.0%)was higher than that of the control group(49.0%),and there was a statistical difference(P<0.01).There was no statistical difference of lesion count for acne,papules and pustules and so on between two groups(P>0.05),and lesion count for acne,papules and pustules and so on in the observation group was significantly lower than that of the control group(P<0.05).All patients had no systemic adverse reactions.There was 2 cases respectively with skin lesion site in drug for exterior use having local redness and itching,tight feeling in the observation group and control group,then patients were asked to reduce the dosage of ointment to continue medication,and patients had no complaint.ConclusionChemical Peel combined with Adapalene Gel for external use treating mild to moderate acne not only can effectively improve the clinical symptom of patients,but also improve their overall quality of life.It is worthy of clinical promotion and application.
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[1] |
黄晓中,朱光也,冯帆,等.5-氨基酮戊酸光动力治疗寻常痤疮的疗效观察[J].中国当代医药,2016,23(25):25-27.
|
[2] |
夏爱爱,唐莉,翟志芳,等.果酸联合盐酸米诺环素治疗中重度痤疮的临床疗效观察[J].中国美容医学,2015,24(9):37-40.
|
[3] |
苏蓓蓓,甘才斌,张晓宁,等.果酸治疗面部轻、中度寻常性痤疮疗效分析[J].中国美容医学,2015,24(22):41-43.
|
[4] |
何春峰,王辉军,柳文红,等.果酸联合丹参酮胶囊治疗中度痤疮疗效评价[J].中国麻风皮肤病杂志,2015,31(12):723-725.
|
[5] |
赵坚钢.果酸联合红蓝光治疗中重度痤疮疗效观察[J].中国美容医学,2015,24(12):59-61.
|
[6] |
袁景奕,牛新武,耿松梅,等.胶原贴敷料联合异维A酸胶丸治疗轻、中度痤疮疗效观察[J].中国皮肤性病学杂志,2011,25(9):691-692.
|
[7] |
董小瑜,杨庭耀.自拟疏肝清肺饮治疗成年女性轻中度痤疮的临床观察[J].中国医药,2014,9(5):735-737.
|
[8] |
黄明欢,黄懿.果酸治疗中度寻常型痤疮疗效及安全性研究[J].中国美容医学,2011,20(1):98-100.
|
[9] |
顾军,李泉,郭志丽.阿达帕林凝胶联合过氧化苯甲酰凝胶治疗寻常痤疮的疗效[J].第二军医大学学报,2003,24 (7):731.
|
[10] |
傅雯雯,方丽,顾军,等.阿达帕林凝胶联合过氧苯甲酰凝胶治疗寻常痤疮的多中心随机对照研究[J].中华皮肤科杂志,2003,36(6):310-312.
|
[11] |
龙福泉,王千秋.夫西地酸乳膏联合阿达帕林凝胶治疗寻常痤疮的临床观察[J].中国皮肤性病学杂志,2012,26 (7):660-662.
|
[12] |
李琳,李恒进,罗燕萍.不同浓度果酸对痤疮丙酸杆菌体外抑菌作用的实验研究[J].中国麻风皮肤病杂志,2007,23(6):482-483.
|
[13] |
赵辨.临床皮肤病学[M].3版.南京:江苏科学技术出版社,2001:935-938.
|
[14] |
中国医师协会皮肤科医师分会《中国痤疮治疗指南》专家组.中国痤疮治疗指南[J].临床皮肤科杂志,2008,37 (5):339-342.
|
[15] |
李惠林,李金花.痤疮的中医药临床及实验研究进展[J].中国美容医学,2010,19(5):258-259.
|
|
|
|