同步放化疗和单纯放疗治疗食管癌的近期效果及其对患者免疫功能的影响

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Abstract ObjectiveTo evaluate short-term effects of concurrent chemoradiotherapy and radiotherapy alone for esophageal cancer and its effect on immune function.MethodsEighty patients with esophageal cancer admitted in our hospital from April 2013 to March 2016 were randomly divided into control group and observation group,40 cases in each group.Patients in the control group received radiotherapy alone,while patients in the observation group were given concurrent chemoradiotherapy.Short-term efficacy,immune function index(NK,Ts,Th,Th/Ts and total T cells)before and after treatment in two groups were compared.ResultsEffective rate in the observation group was 90.0%,significantly higher than 65.0%in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the immune function between two groups before treatment(P＞0.05).After treatment,Th,Th/Ts,and total T cells was significantly lower than that in the control group(P＜0.05),but there was no significant difference in NK and Ts between two groups(P＞0.05).ConclusionConcurrent chemoradiotherapy is an effective treatment for esophageal cancer,which can improve the immune function of patients,but also has significant results.

Key words： Radiotherapy Chemotherapy Esophageal cancer Immune function

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	ZHANG Xiao-xiao

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ZHANG Xiao-xiao. Short term effect of concurrent chemoradiotherapy and radiotherapy alone for esophageal carcinoma and its effect on immune function[J]. 中国当代医药, 2017, 24(2): 64-66.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I2/64

[7]	吴建华，梁国华.热放疗、放化疗和单纯放疗治疗食管癌的临床疗效比照分析[J].中外医疗，2014，33（30）：44-45.
[8]	鲍启德，孙李凌，周利霞.序贯放化疗治疗对食管癌预后及生活质量改善效果观察[J].中国医学工程，2015，23（4）：117.
[9]	强勇，杨楠，董国华，等.紫杉醇联合顺铂新辅助化疗对Ⅲ期食管癌手术风险及预后的影响[J].临床肿瘤学杂志，2016，21（2）：166-169.
[10]	郑敏，叶清，杨成广，等.MUC1表达与食管癌细胞对紫杉醇及顺铂反应的关系[J].中国临床医学，2014，21（1）：1-4.
[11]	吕江，寿文祥.热疗联合同步放化疗对中晚期食管癌的临床疗效及其对血清血管内皮生长因子的影响[J].中国临床药理学杂志，2015，31（16）：1600-1602.
[12]	朱琪伟，黄灿红，万志龙，等.奈达铂同步放化疗治疗老年食管癌的疗效观察[J].中国医药，2013，8（5）：643-645.
[13]	陆文斌，于静萍，倪新初，等.食管癌患者放化疗中病理反应与血清VEGF变化的关系及其对疗效和预后的影响[J].中华放射医学与防护杂志，2013，33（3）：299-302.
[14]	朱琳燕.食管癌患者实施放化疗前后血管内皮生长因子改变与病理反应对预后疗效的影响分析[J].安徽医药，2015，19（1）：70-73.
[15]	李超，骆志国，孙仁煌.同步放化疗对老年食管癌的临床疗效观察[J].中国医学装备，2016，13（8）：51-54.
[1]	刘佳，王卫华.紫杉醇联合顺铂同步放化疗治疗中晚期食管癌疗效分析[J].中国现代药物应用，2015，9（8）：136-137.
[2]	赵宇锋.Ⅲ期食管癌同步放化疗与序贯性放化疗疗效对比分析[J].现代诊断与治疗，2014，25（5）：1091-1092.
[3]	杨健筌，郭文，李光明.同步放化疗与序贯放化疗对食管癌预后影响的Meta分析[J].实用癌症杂志，2016，31（4）：588-594.
[4]	张阿桥.食管癌同步放化疗的临床研究[J].中国医药指南，2013，11（9）：55-56.
[5]	杨灵，李小兵，李丹旦，等.同步放化疗治疗中晚期中上段食管癌的临床观察[J].中国当代医药，2014，21（5）：89-91.
[6]	罗志强，黄燕，康恭礼，等.60例Ⅲ期食管癌三维适形放疗同步化疗与单纯放疗的疗效比较[J].中国现代医生，2014，52（31）：154-156.