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Analysis of detection results of Mycoplasma pneumoniae antibody among 29 243 children aged from 0 to 14 years in Chenzhou Area |
SHI Wen-yuan1 WU Yi2 WU Zhi-jian1▲ HE Zhi-gang1 LI Sheng-tao1 XU Yu-juan1 CAO Hong1 |
1.Center for Laboratory Medicine,the First People′s Hospital of Chenzhou City in Hunan Province,Chenzhou 423000, China;
2.Department of Laboratory,People′s Hospital of Hunan Province,Changsha 410000,China |
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Abstract Objective To investigate and analyse the detection results of Mycoplasma pneumoniae(MP)antibody among children with respiratory tract infection in Chenzhou Area,and to provide an important evidence for the diagnosis and treatment of the disease.Methods MP antibody were detected among 29 243 patients with respiratory symptoms,aged from 0 to 14 years,treated in Chenzhou Children′s Hospital from March 2015 to February 2016 by using passive agglutination method.Meanwhile,the positive rate of MP antibody for different ages and seasons were also analyzed.Results Among the 29 243 cases of children with respiratory tract infection,10 892 cases of MP antibody test results were positive,the positive rate was 37.25%.There was significant difference between the four seasons antibody positive rate,the positive rate of autumn and winter(43.27%,42.15%)was significantly higher than that in spring and summer seasons(34.82%,29.74%), with significant difference(P<0.01).The positive rate of antibody of female children(44.53%)was higher than that of male children(32.67%),with significant difference(χ2=417.26,P<0.01).In the 5 age groups,the antibody positive rate of 7-14 years old children was significantly higher than that other age groups,in the group of 0-28 days,the antibody positive rate was 6.10%,which was significantly lower than that the other groups,with significant difference(P<0.01).The rate of children with MP antibody titer 1∶40 in 0-28 days group and>28 days-<1 year were 50.53%and 52.78%,which was higher than that of 4-6 years(36.05%)and 7-17 years old children group(33.52%),with significant difference(P<0.01).The rate of children with MP antibody titer≥1∶160 in 7-14 years group was 16.60%,which was higher than that of>28 day-<1 year(9.44%),1-3 years(12.36%)and 4-6 years (14.49%).Conclusion The incidence rate of MP infection in children in Chenzhou is high,and it is more common in autumn and winter seasons.It is necessary to strengthen the clinical diagnosis and control of MP infection.
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[1] |
杨加尉.儿童肺炎支原体脑炎研究进展[J].国际儿科学杂志,2015,42(1):87-89.
|
[2] |
Zhang H,Lv G,Shang Y,et al.Changes of airway reactivity after Mycoplasma pneumoniae infection in children:a study for early precautions against pediatric asthma[J].Iran J Allergy Asthma Immunol,2015,14(5):476-82.
|
[3] |
孙雨,王华.儿童肺炎支原体脑炎的诊断和治疗进展[J].医学综述,2015,21(9):1633-1635.
|
[4] |
Medjo B,Atanaskovic-Markovic M,Radic S,et al.Mycoplasma pneumoniae as a causative agent of community-acquired pneumonia in children:clinical features and laboratory diagnosis[J].Ital J Pediatr,2014,18(40):104.
|
[5] |
陈志敏.肺炎支原体肺炎的再认识——从发病机制到临床治疗的探讨[J].中国实用儿科杂志,2012,27(4):253-257.
|
[6] |
Wang Z,Li YC,Chen L.Early identification of refractory Mycoplasma pneumoniae pneumonia in children[J].Zhongguo Dang Dai Er Ke Za Zhi,2015,17(11):1189-1192.
|
[7] |
Ma YJ,Wang SM,Cho YH,et al.Clinical and epidemiological characteristics in children with community-acquired Mycoplasma pneumonia in Taiwan:a nationwide surveillance[J].J Microbiol Immunol Infect,2015,48(6):632-638.
|
[8] |
谢辉,李基明,张慧芬.肺炎支原体抗体和载量指数在儿童肺炎支原体肺炎诊断中的应用[J].中国当代儿科杂志,2016,18(10):984-987.
|
[9] |
卢永芳,王洋真,陈键.两种方法检测肺炎支原体抗体的比对分析[J].医学理论与实践,2016,29(20):3539-3540.
|
[10] |
DeAntonio R,Yarzabal JP,Cruz JP,et al.Epidemiology of community-acquired pneumonia and implications for vaccination of children living in developing and newly industrialized countries:a systematic literature review[J].Hum Vaccin Immunother,2016,12(9):2422-2440.
|
[11] |
段正军,陈锡莲,杨勇卫,等.516例血清标本肺炎支原体抗体检测结果分析[J].国际检验医学杂志,2016,37(8):1115-1116.
|
[12] |
张海琼.柳州市14179例呼吸道感染患儿肺炎支原体感染情况分析[J].现代预防医学,2016,43(10):1790-1791,1800.
|
[13] |
田云粉,李利.昆明市儿童感染肺炎支原体流行病学调查分析[J].昆明医科大学学报,2016,37(1):56-59.
|
[14] |
郑曦.儿童急性呼吸道感染肺炎支原体抗体检测结果分析[J].中华医院感染学杂志,2013,23(14):3433-3435.
|
[15] |
廖春盛,戴小波,刘建军.呼吸道感染患者肺炎支原体检测的临床意义[J].国际检验医学杂志,2011,32(13):1474-1475.
|
[16] |
李东明,黄子殷,张硕,等.2011-2014年南宁地区肺炎支原体感染监测分析[J].中国妇幼保健,2016,31(8):1677-1678.
|
[17] |
陈艳露,宋俊杰.1293例肺炎支原体抗体血清学检测结果分析[J].国际检验医学杂志,2013,34(28):2470-2471.
|
[18] |
Yan T.Role of anti-inflammatory cytokines in pathogenesis of pediatric Mycoplasma pneumoniae pneumonia[J].J Biol Regul Homeost Agents,2016,30(2):541-545.
|
|
|
|