|
|
|
| Clinical analysis of Benazepril combined with Metoprolol in the treatment of heart failure with dilated cardiomyopathy |
| XU You-fan |
| Department of Cardiovascular Medicine,Houjie Hospital of Dongguan City in Guangdong Province,Dongguan 523000, China |
|
|
|
|
Abstract Objective To explore the clinical effect of Benazepril combined with Metoprolol in the treatment of heart failure with dilated cardiomyopathy.Methods The clinical data of 60 patients were suffered from heart failure with dilated cardiomyopathy treated in Department of Cardiovascular Medicine,Houjie Hospital of Dongguan from January 2014 to January 2016 were analyzed.According to different therapeutic regimens,they were evenly divided into two groups,control group(Digitalis with Metoprolol,n=30)and observation group(Benazepril with Metoprolol,n=30).The cardiac function and pulmonary function before and after therapy in heart failure patients with dilated cardiomyopathy were observed.The clinical effect of patients suffering from heart failure with dilated cardiomyopathy in the two groups was also observed.Results There was no significant difference in left atrial diameter,left ventricular end diastolic diameter,left ventricular ejection fraction,6 min walking distance,FEV1,FEV1/FVC,or FEV1%before treatment in the two groups(P＞0.05).After therapy,all indexes in the two groups were both better than those before treatment,and these indexes in the observation group after therapy were better than those in the control group(P＜0.05).The total clinical thera peutic effective rate of observation was higher than that of control group,with statisticant difference(P＜0.05).Conclusion Combination of Benazepril and Metoprolol in the treatment of heart failure patients with dilated cardiomyopathy can significantly improve cardiac function,pulmonaryfunction,and improve clinical efficacy,which is worthy of clinical promotion and application.
|
|
|
|
|
|
| [1] |
张宁，王颖，刘衍霖.贝那普利对慢性心力衰竭患者的临床疗效及预后影响[J].国际医药卫生导报，2015，21（10）：1422-1423.
|
| [2] |
Caruso R，De Chiara B，Campolo J，et al.Neopterin levels are independently associated with cardiac remodeling in patients with chronic heart failure[J].Clin Biochem，2013，46（1-2）：94.
|
| [3] |
陈福生，罗莘，蒲晓群，等.贝那普利对慢性心力衰竭患者血清和肽素及N端脑钠肽前体的影响[J].中国综合临床，2014，30（1）：48-51.
|
| [4] |
岳喜平.美托洛尔、贝那普利和氨体舒通联用治疗慢性充血性心力衰竭临床疗效分析[J].中国医药科学，2011，1（22）：76-77.
|
| [5] |
Kaneshiro T，Suzuki H，Yamada S，et al.Intrathoracic impedance changes reflect reverse left ventricular remodeling in response to cardiac resynchronization therapy in chronic heart failure patients[J].Int Heart J，2012，53（4）：249.
|
| [6] |
韩红梅.贝那普利与美托洛尔合用治疗慢性充血性心力衰竭的临床研究[J].医学综述，2012，18（7）：1092-1093.
|
| [7] |
Borovkova NJ，Kuznccova TE，Borovkov NN，et al.Therapy of arterial hypertension in patients with chronic heart failure and signs of chronic kidney disease with fixed perindopril/ amlodipine combination[J].Kardiologiia，2015，55（6）：22-26.
|
| [8] |
张华，牛方清.卡维地洛联合贝那普利治疗慢性心力衰竭的疗效观察[J].中国现代医生，2015，53（32）：35-37.
|
| [9] |
Milazzo V，Maule S，Di Stefano C，et al.Cardiac organ damage and arterial stiffness in autonomic failure：comparison with essential hypertension[J].Hypertension，2015，66（6）：1168-1175.
|
| [10] |
程长生.贝那普利联合美托洛尔治疗老年原发性高血压合并心力衰竭观察[J].江西医药，2015，50（4）：334-336.
|
| [11] |
中华医学会心血管病学分会，中华心血管病杂志编辑委员会．中国心力衰竭诊断和治疗指南2014[J].中华心血管病杂志，2014，42（2）：98-122.
|
| [12] |
杨国锋.老年原发性高血压合并心衰采用贝那普利联合美托洛尔治疗的临床分析[J].中国现代医生，2014，52（36）：33-35.
|
| [13] |
罗功汶.贝那普利联合美托洛尔对慢性心力衰竭患者心功能和生活质量的影响[J].现代中西医结合杂志，2014，23（25）：2771-2773.
|
| [14] |
刘建飞.高血压合并心力衰竭患者发生心律失常危险因素分析[J].中华实用诊断与治疗杂志，2014，28（4）：372-373.
|
| [15] |
李洪寅，兰海燕，李更新，等.贝那普利、美托洛尔联合螺内酯治疗老年舒张性心力衰竭的疗效与安全性[J].现代中西医结合杂志，2014，23（31）：3472-3474.
|
| [16] |
魏英贤.贝那普利联合美托洛尔治疗老年原发性高血压合并心力衰竭疗效观察[J].中华实用诊断与治疗杂志，2016，30（10）：1036-1038.
|
|
|
|
