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Significance of serum tumor markers in the diagnosis and differential diagnosis of pelvic benign and malignant gynecological tumors |
WU Jie-ru |
Department Clinical Laboratory,Maternal and Child Health Hospital Laboratory in Jiangxi Province,Nanchang 330006,China |
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Abstract Objective To investigate the diagnosis and differential significance of serum tumor markers in pelvic benign and malignant gynecological tumors.Methods Fifty patients with pelvic gynecologic tumor in our hospital from July 5 to December 23,2016 were selected as the research object,According to the nature of the tumor was divided into benign and malignant group(25 cases),and 50 healthy subjects were taken as control group.All patients were given serum tumor markers to detect the detection of positive and biochemical indicators.Results The positive rate of CA153,CA125 of malignant group were 52.00%,92.00%,higher than the benign group(4.00%,60.00%),the difference was statistically significant(P<0.05),The positive rate of CEA,AFP,CA199 in the two groups had,no significant difference(P>0.05);CEA,AFP of the three groups had no statistical significance(P>0.05).In the malignant groups,CA199,CA153,CA125,respectively were[(150.89±7.06),(107.57±4.24),(446.19±10.07)U/ml],benign tumor group [(44.31±3.82),(17.15±1.38),(52.43±5.65)U/ml],were higher than[12.19±0.93),(8.02±0.46),(15.02±2.18)U/ml] of the control group,was statistically significant(P<0.05).Conclusion The detection of serum tumor markers in the diagnosis of pelvic benign and malignant gynecological tumors has a high clinical value and is favorable to the development of treatment regimens.
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