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Clinical value of Tirofiban Hydrochloride in emergency percutaneous coronary intervention in patients with acute myocardial |
FENG Ji1 LIU Juan-feng1 YAN Mei-jun2 |
1.Department of Cardiology,the First People′s Hospital of Jingdezhen City in Jiangxi Province,Jingdezhen 333000,China;
2.Medical Dispute Mediation Office,the First People′s Hospital of Jingdezhen City in Jiangxi Province,Jingdezhen 333000,China |
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Abstract Objective To investigate clinical value of Tirofiban Hydrochloride in emergency percutaneous coronary intervention in patients with acute myocardial.Methods 112 patients with acute myocardial treated emergency percutaneous coronary intervention in our hospital from August 2014 to August 2016 were selected and divided into the control group and the observation group according to random number table method,56 cases in each group.The control group was treated with conventional treatment,the observation group was given combination with Tirofiban Hydrochloride.The condition of blood flow,cardiac function,indicator repeat time,adverse events were compared between two groups.Results After treatment,TIMI blood flow of infarct related vessels and cardiac function improved in the two groups (P<0.05).TIMI blood flow of infarct related vessels and cardiac function improvement in the observation group after treatment were better than those in the control group (P<0.05).Recovery time of ST segment,occurrence time of myocardial enzyme peak in the observation group were earlier than those in the control group (P<0.05).Hospitalization time in the observation group was less than that in the control group (P<0.05).The incidence of adverse events (intraoperative slow flow,reperfusion arrhythmia,bleeding,thrombocytopenia) in the observation group were lower than those in the control group (P<0.05).Conclusion As emergency percutaneous coronary intervention in patients with acute myocardial,tirofiban hydrochloride can improve TIMI blood flow and cardiac function,which can also reduce the risk of adverse events.
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