适形调强放疗+口服卡培他滨对Ⅱ、Ⅲ期直肠癌术后患者的治疗效果

Abstract
Figure/Table
References
Related Citation (0)

Download: PDF (377 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study and analyze the treatment effects of conformal intensity-modulated radiation therapy and oral Capecitabine for postoperative care of patients with stage Ⅱ and Ⅲ rectal cancer.Methods 86 cases of patients with stage Ⅱ and Ⅲ of rectal cancer and who received the treatment in our hospital from February 2013 to March 2015 were selected,and the patients were randomly divided into study group and control group,with 43 cases in each group.All the selected patients were implemented the routine surgery treatment,and the study group were implemented conformal intensity-modulated radiotherapy combined with Capecitabine,while the control group were only treated with conformal intensity-modulated radiation therapy.Then,the clinical effect of two groups was evaluated and analyzed.Results The treatment efficiency in the study group was 83.72%,which was significantly higher than that in the control group of 62.79%,with statistical significance (P<0.01);the disease-free survival rate, overall survival rate and local recurrence rate after the operation for 2 years in the study group were significantly better than those in the control group, with statistical significance (P<0.05).And the incidence of adverse reactions in the study group was 44.19%,which was significantly lower than that in the control group of 65.12%, with statistical significance (P<0.01).Conclusion The treatment effects of conformal intensity-modulated radiotherapy combined with Capecitabine oral administration for patients with stage Ⅱ and Ⅲ rectal cancer,which it has significant clinical effect.

Key words： Rectal cancer Stage Ⅱ and Ⅲ Conformal intensity-modulated radiotherapy Capecitabine

Received: 07 July 2017

PACS:

R735.37

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Sui-hua
	LUO Jin-xian

Cite this article:

LI Sui-hua,LUO Jin-xian. Treatment effect of conformal intensity-modulated radiation therapy and oral Capecitabine for patients with stage Ⅱ and Ⅲ rectal cancer in postoperative nursing[J]. 中国当代医药, 2017, 24(24): 39-41.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I24/39

[1]	朱卫国,韩济华,李涛,等.三维适形放疗并FOLFOX6方案治疗直肠癌术后局部复发前瞻性研究[J].实用医学杂志,2010,26（13）：2343-2346.
[2]	李显蓉,杨庆强,徐林霞,等.腹腔镜手术在老年直肠癌患者中的应用及围手术期护理[J].实用医学杂志,2012,28（1）：150-153.
[3]	肖林,祝喻甲,邱波,等.局部进展期直肠癌术前3DCRT或VMAT同期化疗后肠壁残余癌细胞分布比较[J].中华放射肿瘤学杂志,2016,25（7）：708-712.
[4]	弋振营,李宁,高岭,等.调强适形放射治疗联合替吉奥化学治疗直肠癌术后放疗后局部复发性直肠癌的临床疗效及安全性分析[J].转化医学电子杂志,2015,28（6）：26-27.
[5]	叶卫华,王贵英,韩若凌,等.经直肠超声在评价直肠癌术前新辅助放化疗疗效中的价值[J].中国超声医学杂志,2013, 29（4）：351-354.
[6]	莫凯岚,陈斯泽,钟毓平,等.调强适形放疗同步化疗联合内生场热疗治疗复发和局部晚期直肠癌的近期疗效[J].广东医学,2015,21（16）：2467-2470.
[7]	陈世梅,李莉.XELOX方案同期化疗联合调强适形放疗治疗复发和局部晚期直肠癌的护理[J].肿瘤预防与治疗,2011,24（4）：176-179.
[8]	胡克,庞廷田,杨波,等.直肠癌术前放疗中三维适形放疗与调强适形放疗的剂量学比较分析[J].中华放射医学与防护杂志,2010,30（3）：310-313.
[9]	丁叔波,胡望远,黎萍,等.局部晚期直肠癌新辅助治疗同期加量调强与三维适形放疗随机对照研究[J].中华放射医学与防护杂志,2016,36（4）：283-287.
[10]	廖盛日,范智慧,严昆,等.经直肠超声对放化疗后直肠癌浸润深度判断价值探讨[J].中国超声医学杂志,2012, 28（3）：259-262.
[11]	刘晓平,周小青,邓伟,等.直肠癌白细胞介素-6的表达与临床病理因素的相关性研究[J].中国现代医学杂志,2016,26（6）：23-26.
[12]	肖若冰,肖雅莉,谢海辉,等.直肠癌术前卡培他滨联合两种周期放疗方案疗效研究[J].中国现代医学杂志,2014, 24（4）：62-65.
[13]	依力哈木,马合木提江,亚力坤,等.放射治疗对直肠癌细胞凋亡及相关调控蛋白的影响[J].中国现代医学杂志,2010,20（20）：3118-3121.
[14]	孙彩萍,王建芳,叶万立,等.直肠癌术后调强放疗和适形放疗靶区剂量学研究及危及器官毒性观察[J].中国现代医学杂志,2014,24（1）：54-57.
[15]	孔刚,刘虹,龚志军,等.贝伐单抗联合XELOX方案诱导化疗对局部晚期直肠癌有效性及安全性的临床观察[J].中国现代医学杂志,2015,25（3）：86-90.