双侧子宫动脉上行支结扎联合米索前列醇在产后出血患者中的应用及对凝血因子的影响

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Abstract Objective To investigate the application of bilateral ascending uterine artery ligation combined with Misoprostol in patients with postpartum hemorrhage and its effect on coagulation factor.Methods 68 patients with postpartum hemorrhage treated in our hospital from October 2015 to October 2016 were selected as subjects and were divided into two groups by random number table method,34 cases in each group.The patients of control group were treated with B-Lynch suture,while the patients of observation group were treated with bilateral ascending uterine artery ligation combined with Misoprostol.Coagulation factor were detected before and after the treatment.Hemostatic effect,postoperative recovery and complications were compared between two groups.Results The success rate of hemostasis in the observation group was higher than that in the control group,the amount of bleeding and blood transfusion were less than those in the control group,the operation time and the length of hospital stay were shorter than those in the control group,and the differences were statistically significant (P<0.05).The lochia exposure time and postpartum menstrual cycle of patients in the observation group was shorter than those in the control group,menstruation after tide time was earlier than that in the control group,the differences were statistically significant (P<0.05).After treatment,the levels of Ang Ⅱ,clotting factor Ⅷ and clotting factor Ⅸ of patients in two groups were higher than before the treatment,the differences were statistically significant (P<0.05).After treatment,the levels of Ang Ⅱ,clotting factor Ⅷ and clotting factor Ⅸ of patients in observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Conclusion The application of bilateral uterine artery ligation combined with Misoprostol in patients with postpartum hemorrhage is significant effect,which can significantly improve coagulation factor status and help to control bleeding.

Key words： Misoprostol Postpartum hemorrhage Coagulation factor Influence

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WU Yu-liang. Application of bilateral ascending uterine artery ligation combined with Misoprostol in patients with postpartum hemorrhage and its effect on coagulation factor[J]. 中国当代医药, 2017, 24(36): 66-68转71.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I36/66

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