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| Effect of different mechanical ventilation modes on hemodynamics of neonatal meconium inhalation syndrome |
| ZHANG Wen-ming LI Chi-wang |
| Department of Neonatology,Meizhou People′s Hospital,Guangdong Province,Meizhou 514031,China |
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Abstract ObjectiveTo explore the effect of different mechanical ventilation patterns on hemodynamics of neonatal meconium aspiration syndrome.MethodsA total of 104 cases of neonatal meconium aspiration syndrome from January 2014 to July 2016 in our hospital were selected as the study object,they were divided into conventional ventilation group and high frequency ventilation group by random number table,each group of 52 cases.The conventional ventilation group was treated by constant frequency mechanical ventilation,the high frequency ventilation group was treated by high frequency oscillating mechanical ventilation.The effective rate,time of ventilator,hospitalization time were compared between the two groups;the pressure of oxygen,the partial pressure of carbon dioxide,the stroke volume and the pulse index before and after treatment were compared between the two groups.ResultsThe total effective rate of the high frequency ventilation group was higher than that of the conventional ventilation group (P＜0.05).The time of ventilator,hospitalization time of the high frequency ventilation group were shorter than those of the conventional ventilation group(P＜0.01).The oxygen partial pressure,carbon dioxide partial pressure,stroke volume and pulse index were similar in the two groups before treatment(P＞0.05);the partial pressure of oxygen and the partial pressure of carbon dioxide in the high frequency ventilation group were significantly better than those in the conventional ventilation group (P＜0.05).There was no significant difference in stroke volume,pulsatility index and before treatment between the two groups(P＞0.05).ConclusionThe high frequency mechanical ventilation model can improve the hemodynamics of neonatal meconium aspiration syndrome,improve the results of blood gas analysis,shorten the time of ventilator treatment and the time of hospitalization,and improve the prognosis of children.
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| [2] |
郑继峰.常频机械通气与高频机械通气治疗新生儿呼吸窘迫综合征、新生儿胎粪吸入综合征、新生儿气胸的对比性研究[D].泰安：泰山医学院，2014.
|
| [1] |
Fanos V，Caboni P，Corsello G，et al.Urinary1H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis[J].Early Hum Dev，2014，90（Suppl.1）：S78-S83.
|
| [3] |
Ramanathan P，Wei J，Martin IC，et al.An integrated genomics approach to identify genetic regions associated with neonatal growth trait in mice[J].Anim Biotechnol，2014，25（1/4）：85-97.
|
| [4] |
杜欢.新生儿呼吸机相关性肺炎危险因素及病原学分析[D].石家庄：河北医科大学，2014.
|
| [5] |
滕岚.肺表面活性物质联合呼吸机治疗新生儿胎粪吸入综合征[J].实用中西医结合临床，2014，14（6）：56-57.
|
| [6] |
方锦平，卢小蕴，夏巧湘，等.气管内不同肺表面活性物质用药方案对重症胎粪吸入综合征患儿肺氧合功能指标、有创机械通气时间及并发症风险的影响[J].现代实用医学，2016，28（12）：1611-1612.
|
| [7] |
杨传忠.新生儿常见肺疾病的呼吸支持策略[J].中国小儿急救医学，2014，21（10）：622-628.
|
| [8] |
Vogt MC，Paeger L，Hess S，et al.Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding[J].Cell，2014，156（3）：495-509.
|
| [9] |
林丽君，叶建敏，管敏昌，等.同步间歇指令通气辅以压力支持治疗新生儿胎粪吸入综合征的效果与护理[J].中华现代护理杂志，2014，20（14）：1736-1738.
|
| [10] |
冯云云.一氧化氮吸入治疗新生儿胎粪吸入综合征合并Ⅱ型呼吸衰竭的临床研究[D].新乡：新乡医学院，2014.
|
| [11] |
Le CN，Garey DM，Leone TA，et al.Impact of premedication on neonatal intubations by pediatric and neonatal trainees[J].J Perinatol，2014，34（6）：458-460.
|
| [12] |
徐鸣浩，刘成军，许峰，等.高频振荡通气联合肺表面活性物质治疗重症胎粪吸入综合征的临床研究[J].中华临床医师杂志（电子版），2015，9（18）：3457-3460.
|
| [13] |
周琴芳，廖东，周炳龙，等.无创机械通气联合氨溴索治疗新生儿胎粪吸入综合征的疗效[J].右江医学，2016，44（2）：179-182.
|
| [14] |
Sahota N，Burbridge BE，Duncan MD，et al.Radiation safety education reduces the incidence of adult fingers on neonatal chest radiographs[J].J Radiol Prot，2014，34（2）：333-338.
|
| [15] |
刘凌俊.高频振荡通气与常频机械通气治疗新生儿胎粪吸入综合征的疗效比较[J].中国处方药，2016，14（7）：137-138.
|
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