ObjectiveTo study correlation study on serum resistin in postmenopausal female with cerebral infarction.Methods40 patients of female cerebral infarction who received：therapy from June 2015 to June 2016 in our hospital were selected as research objects,and 40 female patients who were admitted to our hospital during the same period were selected as control group,they all were menopause.The serum resistin,fasting insulin,blood pressure,blood glucose,blood lipids,high sensitive C reactive protein(hs-CRP)and insulin sensitivity were compared between the two groups.ResultsThere were significant differences in systolic blood pressure (SBP),diastolic pressure (DBP),serum resistin,insulin,insulin sensitivity,fasting plasma glucose (FBG),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol(LDL-C),hs-CRP between the two groups(P＜0.01)and there was no significant difference in the triglyceride(TG),total cholesterol(TC)between the two groups(P＞0.05).In the f single factor analysis,the serum resistin was positively correlated with SBP,DBP,insulin,FBG,LDL-C and hs-CRP (P＜0.05),and negatively correlated with insulin sensitivity and HDL-C (P＜0.05).Resistin as a dependent variable,the remaining indicators as independent variables,in the multivariate analysis,the serum resistin was positively correlated with insulin SBP,LDL-C and hs-CRP (P＜0.05),and negatively correlated with insulin sensitivity and HDL-C(P＜0.05).ConclusionIn the postmenopausal female with cerebral infarction,serum resistin levels were significantly increased,the cause of the increase may be related to the inflammatory activation in vivo.