中药坤泰胶囊联合激素替代疗法治疗卵巢早衰的临床效果

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Abstract ObjectiveTo explore the clinical efficacy of traditional Chinese medicine Kuntai Capsule combined with hormone replacement therapy in the treatment of premature ovarian failure.MethodsThe clinical data integrity of 68 cases with premature ovarian failure treated in our hospital from January 2012 to June 2016 were analyzed retrospectively,and 33 patients treated from January 2012 to December 2014 were treated as the hormone group,and hormone replacement therapy was used only;35 patients treated from January 2015 to June 2016 were selected as the combined group,and they were added to Kuntai Capsule on the basis of the hormone group.The levels of sex hormone FSH,E2and clinical effects were compared between the two groups before and after treatment.ResultsThe K scores of the two groups after treatment at 3 months and 3 months after the withdrawal was significantly lower than that before treatment,with signifiacnt difference (P＜0.05).The K scores of the combined group after treatmeng at 3 months and 3 months after the withdrawal was significantly lower than that of the hormone group,with signifiacnt difference(P＜0.05).The level of E2in the combined group after treatment at 3 months and 3 months after the withdrawal was higher than that before treatment and the control group,and the level of FSH in the combined group after treatment at 3 months and 3 months after the withdrawal was lower than that before treatment and in the control group,with signifiacnt difference (P＜0.05).There was no significant difference between the two groups in the total apparent efficiency(P＞0.05).There was significant difference between the two groups in the cure rate (P＜0.05).ConclusionTraditional Chinese medicine Kuntai Capsule combined with hormone replacement therapy in the treatment of premature ovarian failure can improve patients′serum sex hormones levels and the clinical symptoms,achieve good curative effect.

Key words： Premature ovarian failure Kuntai Capsule Sex hormone Hormone replacement therapy Clinical efficacy

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	BAO Xu-dong
	MA Li

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BAO Xu-dong,MA Li. Clinical efficacy of traditional Chinese medicine Kuntai Capsule combined with hormone replacement therapy in the treatment of premature ovarian failure[J]. 中国当代医药, 2017, 24(20): 148-150.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I20/148

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