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Comparison of the clinical effect of somatostatin and Pantoprazole sodium in the treatment of severe acute pancreatitis |
ZHANG Xu |
Department of Critical Care Medicine,Zibo Maternal and Child Health Hospital,Shandong Province,Zibo 255000,China |
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Abstract Objective To compare the effect of somatostatin and Pantoprazole sodium on severe acute pancreatitis.Methods From October 2016 to May 2017,92 patients with severe acute pancreatitis in our hospital were selected and randomly divided into two groups.The Pantoprazole sodium was provided in both control group and research group.On the basis,somatostatin was added in the research group.The clinical effect in the two groups was compared.Results In the research group,the time to wean from mechanical ventilation was (3.26±1.61) d,the average time of gastrointestinal function recovery was (3.26±1.05) d,and abdominal pain relief time was (2.16±1.56) d,which were all shorter compared with those in the control group [(5.64±1.46),(4.62±1.24),(4.64±1.82) d],the differences were statistically significant (P<0.05);3,6 d after treatment,the APACHE-Ⅱscores of the research group were better than the control group,the differences were statistically significant (P<0.05).Conclusion Combination of Pantoprazole sodium and somatostatin can obtain an optimal effect on treating severe acute pancreatitis.
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Received: 19 July 2017
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[1] |
潘树波,耿小平.生长抑素预防内镜逆行胰胆管造影术后胰腺炎效果的Meta分析[J].中华外科杂志,2016,54(6):466-472.
|
[2] |
何小建,张志坚,李达周,等.生长抑素和硝酸甘油预防经内镜逆行胰胆管造影术后胰腺炎的疗效观察[J].中华消化内镜杂志,2014,31(4):206-209.
|
[3] |
胡斌.急性生理和慢性健康状况评分(APACHEⅡ)对重型急性胰腺炎治疗效果观察[J].现代诊断与治疗,2015, 26(21):4939-4941.
|
[4] |
王孝东,吴伯鹏.血必净注射液联合清胰汤治疗重症急性胰腺炎40例[J].西部中医药,2015,28(8):116-118.
|
[5] |
王建军.生长抑素与泮托拉唑钠治疗重症急性胰腺炎的临床效果分析[J].北方药学,2017,14(2):109-109.
|
[6] |
杨美荣,刘斌,张国顺,等.生长抑素联合早期血液灌流治疗急性重症胰腺炎临床分析[J].中华实用诊断与治疗杂志,2017,31(2):145-147.
|
[7] |
丁洪涛,吴玉芳.生长抑素与泮托拉唑钠治疗重症急性胰腺炎的疗效及对血清炎性因子的影响[J].重庆医学,2012, 41(6):552-553,556.
|
[8] |
徐华,陈易,金颖,等.生长抑素及其类似物奥曲肽治疗急性胰腺炎时诱发的低血糖[J].中华胰腺病杂志,2014,14(2):117-119.
|
[9] |
郑建伟,刘应裕,胡小红,等.生长抑素联合泮托拉唑钠治疗重症急性胰腺炎的临床研究[J].现代生物医学进展,2015,15(20):3940-3942.
|
[10] |
沈海涛,梁媛媛,吴娜,等.血液净化时强化生长抑素治疗高脂性重症急性胰腺炎的疗效观察[J].中华急诊医学杂志,2016,25(10):1240-1245.
|
[11] |
阳生光,苏科,朱燕辉,等.肠梗阻导管联合生长抑素治疗重症急性胰腺炎[J].中华急诊医学杂志,2013,22(11):1274-1277.
|
[12] |
姚萍.生长抑素联合泮托拉唑钠治疗重症急性胰腺炎的疗效观察[J].河南医学研究,2013,22(4):540-541.
|
[13] |
吴政洪,陈燕萍,雷创杰,等.生长抑素联合泮托拉唑钠治疗重症急性胰腺炎的疗效观察[J].临床医学工程,2014,21(2):185-186.
|
[14] |
张敏,张庆伟.泮托拉唑钠联合生长抑素治疗重症急性胰腺炎效果观察[J].山东医药,2015,15(40):68-69.
|
[15] |
栗宏斐,陈继红,罗和生,等.神经降压素对胃肠道消化和动力作用的研究进展[J].疑难病杂志,2015,14(6):647-650.
|
[16] |
祝沛沛,彭雷,范才波,等.生长抑素对肝硬化食管胃底静脉曲张破裂出血患者胃肠激素及血流动力学的影响[J].疑难病杂志,2017,16(6):579-583.
|
|
|
|