甲状腺乳头状微小癌颈部淋巴结转移患者术前超声特征的回顾性研究

Abstract
Figure/Table
References (21)
Related Citation (5)

Download: PDF (0 KB) HTML (29 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the characteristics of preoperative ultrasonography in patients with cervical lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTMC). Methods From January 2016 to December 2019, the clinical data of 100 patients with PTMC confirmed by postoperative pathology in our hospital were analyzed retrospectively,31 patients developed CLNM among them. All patients underwent ultrasound examination before operation. The preoperative ultrasound examination data were analyzed.The difference between CLNM and non-CLNM preoperative ultrasound image characteristics was analyzed by univariate analysis, and the independent risk factors of CLNM were analyzed by multivariate Logistic regression. Results Univariate analysis showed that there were no significant difference between the two groups in the location, aspect ratio, shape, internal echo and internal echo components (P＞0.05). There were significant differences between the two groups in maximum diameter of cancer focus, definition of nodal boundary, microcalcification, internal blood flow signal and extracapsular invasion of thyroid (P＜0.05). The results of multivariate Logistic regression analysis showed that the maximum diameter of the cancerous foci ＞5 mm, microcalcification, and extrathyroidal invasion were independent preoperative ultrasound risk signs of CLNM (P＜0.05). Conclusion Preoperative ultrasound signs have a certain predictive value for CLNM in patients with PTMC, among which the maximum diameter of the cancerous foci ＞5 mm, microcalcification and extrathecal thyroid invasion are the high-risk features of CLNM.

Key words： Papillary carcinoma of thyroid Cervical lymph node metastasis Ultrasound characteristics Retrospective study

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZENG Lin-hui

Cite this article:

ZENG Lin-hui. Retrospective study of characteristics of preoperative ultrasonography in patients with cervical lymph node metastasis of papillary thyroid carcinoma[J]. 中国当代医药, 2020, 27(19): 169-171.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I19/169

[1]	Chen W，Zheng R，Baade PD，et al.Cancer statistics in China，2015[J].CA Cancer J Clin，2016，66（2）：115-132.
[2]	肖春莹，周剑宇，杨朝晖，等.超声微血流成像技术与常规彩色多普勒超声评价甲状腺微小癌供应血管及其对甲状腺微小癌预测价值的比较研究[J].中国超声医学杂志，2018，34（12）：23-26.
[3]	黄东航，陈旭，陈兴，等.甲状腺微小乳头状癌细针穿刺标本galectin-3 基因DNA 甲基化检测的价值[J].中国医药科学，2018，8（15）：30-33.
[4]	樊文文，刘利平，张炎晶，等.不同大小甲状腺乳头状癌常规超声及超声造影特征的比较[J].中国当代医药，2018，25（13）：4-7.
[5]	Gao Y，Qu N，Zhang L，et al.Preoperative ultrasonography and serum thyroid-stimulating hormone on predicting central lymph node metastasis in thyroid nodules as or suspicious for papillary thyroid microcarcinoma[J].Tumor Biology，2016，37（6）：7453-7459.
[6]	Lim H，Devesa SS，Sosa JA，et al.Trends in Thyroid Cancer Incidence and Mortality in the United States，1974-2013[J].JAMA，2017，317（13）：1338.
[7]	许德斌，袁春雷，张缤迎，等.甲状腺乳头状癌颈部淋巴结转移特点及清扫策略[J].江西医药，2017，52（10）：966-968.
[8]	Liu X，Medici M，K Wong N，et al.Bethesda Categorization of Thyroid Nodule Cytology and Prediction of Thyroid Ccancer Type and Prognosis[J].Thyroid，2016，26（2）：256-261.
[9]	王志民，刘剑，杜月明，等.高频二维超声及彩色多普勒超声声像图对甲状腺癌颈部淋巴结转移的诊断价值[J].癌症进展，2018，16（13）：52-55.
[10]	汤靖岚，侯春杰，范小明.甲状腺微小乳头状癌中央区淋巴结转移的术前超声预测模型建立[J].中华医学超声杂志（电子版），2019，16（4）：257-263.
[11]	张于芝，丁文波，武心萍，等.临床超声及细胞病理学特征对甲状腺微小乳头状癌中央区淋巴结转移的预测价值[J].中国超声医学杂志，2017，33（11）：964-967.
[12]	兰雨，宋青，金壮，等.常规超声特征及BRAFV600E 基因突变与甲状腺乳头状癌颈部淋巴结转移的相关性[J].解放军医学杂志，2019，44（9）：747-752.
[13]	高立霓，张敏，杨大雁，等.分化型甲状腺癌术前原发肿物超声特征与术后颈部淋巴结转移的关系[J].中国普通外科杂志，2019，28（5）：630-635.
[14]	冯欣宇，张晓鸽，李鹤群，等.甲状腺癌的声像图表现规律及高频超声在甲状腺癌诊断和鉴别诊断中的应用价值[J].实用癌症杂志，2018，33（5）：163-165.
[15]	吴凤姬，黄基柱，张洁.甲状腺良、恶性结节的多普勒超声检查结果分析[J].海南医学，2018，29（1）：77-80.
[16]	孟庆博.结节性甲状腺肿合并甲状腺微小癌的早期诊断方法研究[J].中国当代医药，2016，23（22）：25-27.
[17]	姜雪，黄学忠，祖国，等.甲状腺微小乳头状癌143 例肿瘤大小与超声图像特点关联研究[J].中华肿瘤防治杂志，2019，26（6）：395-399.
[18]	徐迎春，孟利伟，徐潮阳.甲状腺微小乳头状癌颈Ⅲ、Ⅳ区淋巴结转移相关因素分析及清扫方式[J].中国现代医生，2018，56（12）：51-54.
[19]	李瑾，潘印，周剑宇.超声造影与彩色多普勒超声对甲状腺癌淋巴结转移诊断价值[J].医学影像学杂志，2017，27（10）：1879-1882.
[20]	李涛.甲状腺肿块彩色多普勒超声与病理诊断结果的临床对比分析[J].中华肿瘤防治杂志，2018，25（S1）：44-45.
[21]	Xu JM ，Xu HX，Li XL，et al.A Risk Model for Predicting Central Lymph Node Metastasis of Papillary Thyroid Microcarcinoma Including Conventional Ultrasound and Acoustic Radiation Force Impulse Elastography[J].Medicine，2016，95（3）：e2558.