食管支架置入联合适形放疗治疗局部晚期食管癌的临床效果

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Abstract ObjectiveTo investigate the clinical effect of esophageal stent placement combined with conformal radiotherapy in the treatment of local advanced esophageal cancer.MethodsA total of 60 patients with local advanced esophageal cancer were enrolled in the oncology department from January 2014 to April 2016.They were divided into experimental group and control group,and there were 30 cases in each group.Experimental group was treated with stent placement,and then given the conformal radiotherapy,while control group was treated with conformal radiotherapy alone.The radiation methods and dosage in the two groups were the same.Short-term effect(CR+PR),6 months and 1 year survival rate and incidence of treatment-related complications were compared in patients between the two groups after treatment.ResultsThe total effective rate of short-term in experimental group was 93.3%,which was higher than that of control group(70.0%),and the difference was statistically significant(P＜0.05).6 months and 1 year survival rate of experimental group was 90.0%and 76.7%respectively,which were higher than those of control group(66.6%and 50.0%),and the differences were statistically significant(P＜0.05).The incidence of chest pain above classⅡ in experimental group and control group was 26.7%and 6.6%respectively,and the incidence of esophageal restenosis in experimental group and control group was 3.3%and 23.3%respectively after treatment,the incidence of esophageal perforation were 0 and 13.3%respectively,and there was a statistical difference between the two groups(P＜0.05).There was no statistical difference of incidence of esophagitis between the two groups (P＞0.05).ConclusionCompared with simple radiotherapy,esophageal stent placement combined with conformal radiotherapy has a higher the total effective rate of short-term and 1 year survival rate,and a lower the incidence of esophageal perforation and esophageal restenosis and can significantly improve the nutritional status and life quality of patients with advanced esophageal cancer.

Key words： Esophageal cancer Stent placement Conformal radiotherapy

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	Articles by authors
	WAN Lin-lin
	LIU Xiao-hong
	XIONG Yong
	GONG Xiao-bao
	SONG Wei-ping
	RUAN Jiu-gen

Cite this article:

WAN Lin-lin,LIU Xiao-hong,XIONG Yong, et al. Clinical effect of esophageal stent placement combined with conformal radiotherapy in the treatment of local advanced esophageal cancer[J]. 中国当代医药, 2017, 24(23): 58-60.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I23/58

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