经尿道前列腺中叶等离子电切术联合术后非那雄胺治疗高龄高危良性前列腺增生患者的短期临床效果

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Abstract

Objective To investigate the short-term clinical effect of transurethral plasmakinetic resection of mid-lobal of prostate combined with postoperative Finasteride in the treatment of elderly patients with high-risk benign prostatic hyperplasia (BPH).Methods From January 2012 to January 2019, 78 dominated by mid-lobal hyperplasia of elderly patients with high-risk BPH were selected as the study subjects in our hospital.They were divided into group A (39 cases) and group B (39cases) by the random number table method.The methods used in group A and group B were respectively for transurethral resection of the prostate (TURP) and transurethral plasmakinetic resection of mid-lobal of prostate combined with postoperative Finasteride.The operation time, intraoperative blood loss, postoperative hospitalization time, postoperative urinary catheter removal time, postoperative continuous bladder flushing time, incidence of surgical complications and clinical relevant indicators(international prostate symptom score [IPSS], quality of life index [QOL]score, maximum urine flow rate [Qmax],residual urine volume [RUV]and prostate volume [PV])before and after surgery were compared in the two groups.Results The operation time, postoperative hospitalization time, postoperative urinary catheter removal time and postoperative continuous bladder flushing time of patients in the group B were shorter than those in the group A, with statistically significant differences (P<0.05).The intraoperative blood loss of patients in the group B was less than that in the group A, and the difference was statistically significant (P<0.05).The total incidence rates of intraoperative and postoperative complications of patients in the group B were lower than those in the group A, with statistically significant differences (P<0.05).There were no statistically significant differences in IPSS score, QOL score, Qmax, RUV, PV before surgery between the two groups of patients (P>0.05).The IPSS score, QOL score, RUV and PV at 3 and 6 months after surgery in the two groups were lower than those before surgery, and Qmax was higher than that before surgery, with statistically significant differences (P<0.05).The IPSS and QOL scores at 3 and 6 months after surgery in the group B were lower than those in the group A, and Qmax was higher than that in the group, with statistically significant differences (P<0.05).There were no statistically significant differences in RUV and PV between the two groups of patients at 3 months after surgery (P>0.05).The RUV and PV at 6 months after surgery in the group B were lower than those in the group A, with statistically significant differences (P<0.05).Conclusion Short-term effect of transurethral plasmakinetic resection of mid-lobal of prostate combined with postoperative Finasteride to treat elderly patients with high-risk BPH is superior to that of traditional TURP,which can reduce the risk of surgery, improve the quality of life of patients, make better the prognosis of patients.It can provide a new treatment selection strategy for the clinical treatment of elderly patients with high-risk BPH mainly with mid-lobal of prostate hyperplasia.

Key words： Mid-lobal of prostate hyperplasia Transurethral plasmakinetic resection of prostate Transurethral resection of the prostate Finasteride Elderly and high-risk patients

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