The problems and limitations in the teaching of Traditional Chinese medicine research laboratory,such as the lack of Traditional Chinese medicine research hours,difficulty to understanding Traditional Chinese medicine research,little practical application and value recognition,limited teaching mode,were analyzed.We have tried to establish the teaching and practice system for Traditional Chinese medicine scientific research by improving the teaching mode and means.Small class system was established;the application teaching of Traditional Chinese medicine research instruments was strengthened;the practical teaching of molecular biology and pathological examination technology was solidified;open examination paper was used to improve the examination system,and the bottleneck of Traditional Chinese medicine scientific research laboratory teaching was broken through.The above methods not only introduced the advanced Traditional Chinese medicine research knowledge,but also expanded students′ visual field,stimulated students′ interest in learning and enhanced their passion for Traditional Chinese medicine research.As a result,The construction of teaching and practice system in Traditional Chinese medicine scientific research laboratory could help improve the teaching status in the lab,and guide students to learn and grasp the thought methods of TCM scientific research.