Objective Based on literature retrieval and data mining,to analyze the treatment rules of traditional Chinese medicine(TCM)for acute gastrointestinal function injury(AGI),so as to provide clinical reference for drug use.Methods The medical research literature of AGI treatment by TCM in January 1,2010 to December 31,2020 were collected from CNKI、Wanfang and VIP database.According to the inclusion and exclusion criteria，all the literature were screened and the information of prescriptions and medicines were extracted to establish the database.Imported the database into the ancient and modern medical record cloud platform(V2.2.3)and analyzed the frequency,attribute,correlation and complex network of medication.Results A total of 58 prescriptions were included,involving 56 kinds of Chinese medicine.The top five Chinese medicine with the higher frequency of prescriptions were Rhubarb,Magnolia officinalis,Fructus aurantii Immaturus,Mirabilite,Fried Licorice and the average using dose were 12.48 g,13.72 g,12.07 g,11.59 g and 7.42 g.The main property of medicine was warm,cold,flat,and tastes were bitter,pungent and sweet.The main belonged meridians were spleen,stomach and lung.The results of correlation and complex network analysis showed that the core prescription was Dachengqi Decoction combined with Angelica,Codonopsis,Aconite,Fried Atractylodes macrocephala,Fried Licorice.Conclusion The clinical treatment of acute gastrointestinal injury with

TCM could based on Dachengqi Decoction.At the same time，it can be combined with medicines such as warming Yang、invigorating Qi or invigorating the Spleen to obtain better therapeutic effects.