Objective To investigate the clinical effect of Huangqi Jiedu Decoction on recurrence and metastasis of triple negative breast cancer after operation.Methods A total of 56 patients with primary triple negative breast cancer who were treated in Dalian Hospital of Integrated Traditional Chinese and Western Medicine from February 2016 to February 2018 were selected as the research objects and divided into the control group and the observation group by computer random grouping method,with 28 cases in each group.The control group was treated with Paclitaxel periodic chemotherapy or surgery,and the observation group was treated with Huangqi Jiedu Decoction on the basis of the control group.Serum tumor markers,solid tumor volume under computed tomography(CT),adverse reactions and longterm treatment results were compared between the two groups before and after treatment.Results After treatment,the carbohydrate antigen 153(CA153)and carcinoembryonic antigen(CEA)in the observation group were higher than those in the control group,the solid tumor volume under CT was smaller than that in the control group,and the differences were statistically significant(P＜0.05).The total incidence of adverse reactions of the observation group was lower than that of the control group,and the difference was statistically significant(P＜0.05).The recurrence and metastasis rates of observation group at 6,12 and 18 months after treatment were lower than those of the control group,the differences were statistically significant(P＜0.05).Conclusion In the treatment of triple negative breast cancer patients with postoperative recurrence and metastasis,the use of Huangqi Jiedu Decoction can not only effectively reduce the CA153 and CEA values of patients,but also reduce the probability of postoperative adverse reactions,and help to reduce the probability of postoperative recurrence and metastasis.