Abstract： Objective To investigate the types and distribution of pathogenic bacteria, and drug resistance in patients with chronic suppurative otitis media (CSOM). Methods A total of 108 CSOM patients admitted to our hospital from January 2015 to June 2016 were enrolled in this study. The specimens from 108 patients′ secretions were isolated, cultured, identified, performed with sensitivity analysis for antibacterial agents. Results Among 108 patients, 104 ones were detected with pathogens. The detection rate was 96.3%. Microrganism causing CSOM included Gram-positive bacteria in 62 stains (59.6%), Gram-negative bacteria in 33 strains (33.7%) and fungi in 9 strains (8.7%). The main strains were 31 strains of Staphylococcus aureus(29.8%),13 strains of Staphylococcus epidermidis (12.5%),13 strains of Staphylococcus capitis(12.5%),19 strains of Pseudomonas aeruginosa(18.3%)and 8 strains of Proteus mirabilis(7.7%).Analysis of drug resistance showed that Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus capitis were absolutely sensitive to Linezolid, Vancomycin and nitrofurantoin (100.0%) without drug resistance. Pseudomonas aeruginosa and Proteus mirabilis were 100.0% sensitive to Meropenem, Amikacin, Imipenem and Palacetin without drug resistance.Proteus mirabilis were sensitive to various antibiotics with a poor drug resistance. Conclusion The main pathogens causing CSOM are Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus capitis, and Pseudomonas aeruginosa. Different pathogens have different tolerance to antibacterial drugs. Physicians can select appropriate antibacterial agents by identifying the types of pathogens causing otitis media for effective treatment.
郭欣明. 慢性化脓性中耳炎病原菌的分布特征及耐药情况[J]. 中国当代医药, 2019, 26(11): 122-125.
GUO Xin-ming. Distribution characteristics of pathogenic bacteria and drug resistance in chronic suppurative otitis media. 中国当代医药, 2019, 26(11): 122-125.
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