|
|
Effect of Dexmedetomidine nasal drops combined with Dyclonine on the quality of resuscitation in children undergoing transthoracic congenital heart surgery under the guidance of esophageal echocardiography |
WU Guang-hua1 ZHONG Qin-wen1 ZHONG Hui-sheng1 HUANG Xing-xing2 |
1.Operating Room of the Heart Center,the First Affiliated Hospital of Gannan Medical College,Jiangxi Province,Ganzhou 341000,China;
2.Department of Anesthesiology,Ganzhou Oriental Hand and Foot Surgery Hospital,Jiangxi Province,Ganzhou 341000,China |
|
|
Abstract Objective To explore the effect of Dexmedetomidine Nasal Drops combined with Dyclonine on the quality of resuscitation of children undergoing transthoracic congenital heart surgery under the trans esophageal echocardiography (TEE).Methods A total of 50 children who underwent TEE-guided transthoracic small incision atrioventricular septal defect closure surgery admitted to the First Affiliated Hospital of Gannan Medical College from June 2017 to August 2019 were selected as the research objects and divided into the control group and the observation group according to random allocation method,with 25 cases in each group.In the control group,Dyclonine was evenly applied to the front 1/3 of the cannula,and 0.5 mL of physiological saline was dripped into the nostril.In the observation group,the front 1/3 of the tracheal intubation was evenly coated with Dyclonine and Dexmedetomidine 2 μg/kg nasal drip.The mean arterial pressure (MAP),heart rate (HR),and arterial blood oxygen saturation (SpO2) at the end of the operation(T0),immediately after extubation (T1),and 5 minutes after extubation (T2) were recorded in the two groups of children,and the recovery time and the occurrence of adverse reactions were compared.Results The MAP and HR at T0,T1,and T2 of the observation group were lower than those of the control group,and SpO2 was higher than that of the control group,The differences were statistically significant (P<0.05).The total incidence of adverse reactions among children in the observation group was lower than that of the control group,and the difference was statistically significant (P<0.05).The restlessness score and recovery time of children in the observation group were significantly lower than those of the control group,and the differences were statistically significant (P<0.05).Conclusion Dexmedetomidine combined with Dyclonine has better quality and higher safety in resuscitation of children with TEE guided transthoracic congenital heart disease than that of single application of Dyclonine,which can be widely promoted in clinic.
|
|
|
|
|
Cite this article: |
WU Guang-hua,ZHONG Qin-wen,ZHONG Hui-sheng, et al. Effect of Dexmedetomidine nasal drops combined with Dyclonine on the quality of resuscitation in children undergoing transthoracic congenital heart surgery under the guidance of esophageal echocardiography[J]. 中国当代医药, 2021, 28(7): 60-63.
|
|
|
|
URL: |
http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2021/V28/I7/60 |
[1] |
韩胜富,甘耐炎,陈军,等.经胸微创封堵治疗室间隔缺损188例临床分析[J].心血管外科杂志,2018,7(2):209-210.
|
[2] |
张成,张宜乾,王国祥.食管超声引导下经胸微创外科封堵术在先天性心脏病治疗中的临床应用[J].心血管病防治知识(学术版),2018(5):59-61.
|
[3] |
于文波.食管超声引导下经胸微创外科封堵术治疗先天性心脏病的疗效[J].中国民康医学,2018,30(3):10-12.
|
[4] |
陈晓艳.盐酸达克罗宁胶浆联合利多卡因咽喉部喷雾应用于食管扩张术患儿的效果[J].检验医学与临床,2019,16(24):3610-3612,3616.
|
[5] |
赵卫茂.食管超声引导下经胸微创外科封堵术在先天性心脏病治疗中的临床应用价值及安全性分析[J].世界最新医学信息文摘,2019,19(41):111-113.
|
[6] |
汝建芬.右美托咪定联合达克罗宁胶浆在腹腔镜胆囊切除术中应用对患者苏醒期躁动的预防效果[J].临床合理用药杂志,2018,11(5):57-58.
|
[7] |
谭卫华,曾慧,刘健萍,等.FloTrac/Vigileo 监测右美托咪定滴鼻复合七氟醚吸入诱导对先天性心脏病患儿血流动力学的影响[J].现代中西医结合杂志,2018,27(31):3426-3429.
|
[13] |
王霄鹏,吴思思,武海龙.达克罗宁联合利多卡因表面麻醉用于抑制心血管反射的临床效果[J].实用临床医药杂志,2019,23(4):93-95.
|
[8] |
Minaei A,Haghdoost-Yazdi H.Dexmedetomidine attenuates the induction and reverses the progress of 6-hydroxydopamineinduced parkinsonism;involvement of K ATP channels,alpha 2 adrenoceptors and anti-inflammatory mechanisms[J].Toxicol Appl Pharmacol,2009,238(3):191.
|
[9] |
Chen L,Cao J,Cao D,et al.Protective effect of dexmedetomidine against diabetic hyperglycemia-exacerbated cerebral ischemia/reperfusion injury: An in vivo and in vitro study[J].Life Sci,2019,12(235):116 553.
|
[10] |
Qiang S,Xiangwei L,Yuhan S,et al.Role of TLR4/MyD88/NF-κB signaling pathway in coronary microembolizationinduced myocardial injury prevented and treated with nicorandil[J].Biomed Pharmacother,2018,45(106):776-784.
|
[11] |
Zhou ZG,Liu R,Tan HL,et al.The application of dexmedetomidine combined with dezocine in thoracoscopic radical resection of lung cancer and its effect on awakening quality of patients[J].Eur Rev Med Pharmacol Sci,2019,23(17):7694-7702.
|
[12] |
Chu C,Yi X,Sun J,et al.Comparison of anesthetic effects of dexmedetomidine and tramadol,respectively,combined with propofol in percutaneous microwave coagulation therapy for hepatocellular carcinoma[J].Oncol Lett,2019,18(4):3599-3604.
|
[14] |
王加芳,戚忠,祝德刚,等.盐酸达克罗宁胶浆复合丁卡因表面麻醉在电子喉镜下急诊咽喉部异物取出术中的效果观察[J].临床急诊杂志,2017,18(11):860-861.
|
[15] |
刘圆,曾彦茹,许立新,等.达克罗宁胶浆对老年高血压患者全麻诱导气管插管期间应激反应的影响[J].广东医学,2016,37(12):1770-1774.
|
[16] |
陈亮,何文胜,张军,等.达克罗宁胶浆联合右美托咪定对术后导尿管所致膀胱刺激征的影响[J].实用临床医药杂志,2016,20(23):134-135.
|
[17] |
袁静,赵继峰,陈娜.达克罗宁胶浆局部喷洒对内镜下结肠息肉电切术患者肠蠕动的影响[J].实用中西医结合临床,2019,19(11):85-86.
|
[18] |
吕冬梅.全身麻醉患者行经盐酸达克罗宁胶浆涂抹导尿管置入尿道对苏醒期患者躁动的影响[J].临床合理用药杂志,2019,12(31):24-25.
|
[19] |
李若萌.达克罗宁胶浆对快通道房间隔缺损封堵术患者全麻围术期的效果观察[J].海峡药学,2019,31(10):177-178.
|
[20] |
李静静,方萌,邱珍,等.达克罗宁胶浆用于经鼻清醒气管插管的临床意义[J].热带医学杂志,2019,19(9):1107-1110.
|
|
|
|