|
|
|
| Application value of thromboelastography in coagulation dysfunction and judgment of severity of illness of patients with emergency craniocerebral injury |
| ZOU Hai-jun CHEN Chen LI Tian-xing |
| Department of Emergency, People′s Hospital in Sanshui District of Foshan City, Guangdong Province, Foshan 528100,China |
|
|
|
|
Abstract Objective To explore the value of thromboelastography (TEG) on judgment of coagulation dysfunction and the severity of illness in emergency traumatic brain injury.Methods A total of 90 patients with emergency traumatic brain injury admitted from January 2016 to June 2017 from People′s Hospital in Sanshui District of Foshan City were selected as subjects.Ninety patients with craniocerebral injury were divided into high coagulation group (n=50), low coagulation group (n=11) and normal group (n=29) by TEG comprehensive coagulation index (CCI).The severity of craniocerebral injury was assessed by Glasgow coma index (GCS) score in 90 patients, who were divided into severe group (n=32), moderate group (n=42) and mild group (n=16).Plasma prothrombin time (PT), thrombin time (TT), activated partial thrombin time (APTT), fibrin degradation product (FDP) and D-dimer (D-D) were detected.TEG reaction time (R), coagulation time (K), maximum thrombus size (Ma), coagulation angle (α), clot strength (G) and coagulation composite index (CCI) of TEG were measured.TEG and clotting test results were compared.Results The R and K time of the high coagulation group were significantly shorter than those of the low coagulation group and the normal group,and the differences were statistically significant (P<0.05).Ma, α and G in the high coagulation group were significantly higher than those in the low coagulation group and the normal group, and the differences were statistically significant(P<0.05).FDP in the hypercoagulation group was significantly higher than that in the normal group, and the difference was statistically significant (P<0.05).The D-D of the high-coagulation group was significantly higher than that of the low-coagulation group and the normal group, and the differences were statistically significant (P<0.05).R and K time of the severe group were significantly shorter than those of the mild group, and the differences were statistically significant (P<0.05).Ma, α, G, D-D in the severe group were significantly higher than those in the moderate group and mild group, and the differences were statistically significant (P<0.05).Conclusion Compared with the conventional coagulation indexes, the TEG can better distinguish the severity of emergency craniocerebral injury and understand the status of coagulation function more quickly and accurately.
|
|
|
|
|
|
|
|
|
