|
|
Analysis of the clinical effect of microscopic resection combined with conjunctival flap surgery in the treatment of refractory corneal ulcer |
HUANG Hai YANG Tian ZHANG Zhong-sheng |
1.Department of Cornea,Nanchang Aier Eye Hospital,Jiangxi Province,Nanchang 330000,China;
2.Department of Ophthalmology,Nanchang Aier Eye Hospital,Jiangxi Province,Nanchang 330000,China |
|
|
Abstract ObjectiveTo investigate the clinical effect of microscopic resection combined with conjunctival flap surgery in the treatment of refractory corneal ulcer.Methods60 cases of refractory corneal ulcer from April 2015 to April 2017 in our hospital were randomly divided into the control group and the observation group,30 cases in each group.The control group was treated with routine medication,the observation group was treated with microscopic resection combined with conjunctival flap surgery.The clinical efficacy,the incidence rate of complications and visual acuity between the two groups were compared.ResultsThe cure rate of the observation group was 93.33%,which was higher than that of the control group(66.67%),the difference was statistically significant(P<0.05).The incidence rate of secondary glaucoma,corneal perforation,corneal staphyloma,conjunctival flap partial dissolution,conjunctival flap perforation and conjunctival flap slippage in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).The visual acuity of the observation group after treatment was higher than that of the control group,the difference was statistically significant(P<0.05).ConclusionThe clinical effect of microscopic resection combined with conjunctival flap surgery in the treatment of refractory corneal ulcer is significant,which can effectively save the eye,promote the improvement of visual acuity,low complication rate and high safety,it has positive clinical significance.
|
|
|
|
|
[1] |
张雁冰,成霄黎,董静,等.病灶切除联合结膜瓣遮盖术治疗难治性角膜溃疡[J].山西医科大学学报,2010,41(2):169-171.
|
[2] |
雷光明,王喜梅,张新萍.结膜瓣遮盖术治疗难治性角膜溃疡[J].眼科新进展,2011,31(9):883-885.
|
[3] |
中华医学会眼科学分会角膜病学组.感染性角膜病临床诊疗专家共识(2011 年)[J].中华眼科杂志,2012,48(1):72-75.
|
[4] |
王宇雷.深板层角膜切除联合自体全角膜结膜筋膜瓣遮盖术治疗老年严重角膜溃疡[J].中外医疗,2015(22):97-99.
|
[5] |
沈伟锋.角膜清创联合结膜瓣遮盖术治疗真菌性角膜溃疡[J].国际眼科杂志,2012,12(5):839-840.
|
[6] |
苗培建,崔建萍,杨玲,等.羊膜移植与结膜瓣遮盖在角膜溃疡治疗中临床疗效的对比观察[J].国际眼科杂志,2010,10(2):312-313.
|
[7] |
刘志谦.结膜瓣遮盖术治疗难治性角膜溃疡27例[J].山东大学耳鼻喉眼学报,2011,25(3):78-79.
|
[8] |
郑伊春.溃疡灶切除联合结膜瓣遮盖术治疗真菌性角膜溃疡[J].河南科技大学学报(医学版),2008,26(2):135-136.
|
[9] |
王鑫,陈默.羊膜移植联合结膜瓣遮盖术治疗深层细菌性角膜溃疡[J].临床眼科杂志,2017,25(1):61-63.
|
[10] |
杨爱红,杜诚,余其智.结膜瓣遮盖联合睑裂缝合术予规范化药物干预治疗难治性角膜溃疡的疗效观察[J].浙江中医药大学学报,2014,38(2):186-187.
|
|
[11陈乐民,李定章.病灶切除联合结膜瓣遮盖术治疗单纯疱疹病毒性深层角膜溃疡疗效观察[J].中国实用眼科杂志,2013,31(7):919-920.
|
[12] |
付建辉.病灶切除联合结膜瓣遮盖术治疗深层角膜溃疡[J].基层医学论坛,2015,19(29):4102.
|
[13] |
刘卫卫,翟华蕾,程钧,等.角膜溃疡清创联合结膜瓣遮盖术治疗感染性角膜溃疡的临床疗效[J].中华眼视光学与视觉科学杂志,2016,18(2):115-120.
|
[14] |
郭晓飞,肖青,肖凤枝,等.结膜瓣遮盖术治疗难治性角膜溃疡疗效观察[J].中国实用眼科杂志,2016,34(7):735-737.
|
[15] |
谯雁彬,易虹,聂昕.结膜瓣遮盖术治疗难治性角膜溃疡的临床研究[J].重庆医学,2015,44(34):4824-4826.
|
|
|
|