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Effect analysis of Racecadotril in adjuvant treatment of children with acute diarrhea |
HUANG Zhuan-di |
Department of Pediatrics,Dongguan People′s Hospital,Guangdong Province,Dongguan 523000,China |
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Abstract Objective To investigate the clinical effect of Racecadotril in the treatment of children with acute diarrhea.Methods Ninety-six children with acute diarrhea admitted to our hospital from April to October 2018 were selected as research objects and divided into control group and experimental group according to random number table method,48 cases in each group.On the basis of routine treatment,the control group was treated with Montmorillonite Powder and Bifidobacterium Quadruple Viable Tablets,while the experimental group was treated with Racecadotril on the basis of the control group for 5-7 days.After treatment,the clinical effects,clinical symptom grading and quantitative scores and clinical symptom improvement before and after treatment were compared between the two groups.Results The total effective rate of clinical treatment in the experimental group was higher than that in the control group,and the difference was statistically significant (P<0.05).Before treatment,there was no significant difference in clinical symptom grading and quantitative scores between the two groups (P>0.05).After treatment,the clinical symptom grading quantitative scores of the two groups of children were lower than those before treatment,and the anorexia,stool frequency and stool character scores of the experimental group were lower than those of the control group,with statistically significant differences (P<0.05).The fever reduction,vomiting cessation,abdominal pain and distension cessation,stool frequency return to normal and stool character return to normal time in the experimental group were shorter than those in the control group,the differences were statistically significant (P<0.05).Conclusion Racecadotril is effective in the treatment of children with acute diarrhea.which can effectively improve the clinical symptoms of children and shorten the treatment time,and is worthy of clinical promotion and application.
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