术前胆道减黄对肝门部胆管癌手术患者疗效及预后的影响

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Abstract Objective To investigate the influence of preoperative yellow reduction of bile duct on the curative effect and prognosis of hilar cholangiocarcinoma.Methods From March 2015 to March 2017,78 patients with hilar cholangiocarcinoma were selected and randomly divided into the experimental group and the reference group according to the order of treatment,with 39 patients in each group.The patients in the control group were treated with direct hepatectomy,the patients in the experimental group were treated with percutaneous transhepatic bile duct drainage before hepatectomy.The changes of liver function before and after treatment were observed in the experimental group,and the related indexes,postoperative complications and 1 year mortality were analyzed and compared between the two groups.Results The liver function indexes such as TB,ALT,γ-GT and ALP in the experimental group after treatment were all lower than those before treatment,the difference was statistically significant(P＜0.05).There was no significant difference in operative time,hospitalization time and blood transfusion volume between the two groups (P＞0.05),the amount of intraoperative blood loss in the experimental group was less than that in the control group,the difference was statistically significant(P＜0.05).There was no significant difference in postoperative complications and 1-year mortality between the two groups (P＞0.05).Conclusion Preoperative yellow reduction of bile duct can effectively improve liver function of patients with hilar cholangiocarcinoma,but it can not significantly reduce postoperative complications and mortality.Patients with poor preoperative liver function can be treated with selective yellow reduction.

Key words： Hilar cholangiocarcinoma Hepatobiliary drainage Yellow reduction therapy Prognosis

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	LIU Yun-feng

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LIU Yun-feng. Influence of preoperative yellow reduction of bile duct on curative effect and prognosis of patients with hilar cholangiocarcinoma[J]. 中国当代医药, 2019, 26(2): 77-79.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I2/77

[1]	刘新慧.微创胆道减黄对肝门部胆管癌患者疗效及预后的影响研究[J].白求恩医学杂志，2017，15（5）：595-596.
[2]	夏安宁，张守响，邓勇，等.姑息性手术治疗与微创胆道减黄对肝门部胆管癌疗效分析[J].国际外科学杂志，2015，42（11）：190-192.
[3]	李澄云，牛秀峰，倪家连.术前减黄对肝门部胆管癌手术效果的影响[J].肝胆胰外科杂志，2017，29（3）：203-206.
[4]	张树亮，刁美霞.肝门部胆管癌患者术前减黄治疗的近期疗效[J].中国肿瘤临床与康复，2014，18（2）：169-171.
[5]	顾进，涂奎，王芳，等.术前减黄对Ⅲ、Ⅳ型肝门部胆管癌的临床价值[J].吉林医学，2017，38（7）：1330-1331.
[6]	杨阳，李成林，王平，等.术前胆道引流对Ⅲ、Ⅳ型肝门部胆管癌疗效的临床观察[J].重庆医学，2016，45（27）：3852-3854.
[7]	黄长山.肝门部胆管癌术后胆红素的动态变化规律及影响因素分析[J].肝胆外科杂志，2017，25（3）：190-194.
[8]	陆军，童宗培，王俊，等.肝门部胆管癌术后并发症发生危险因素分析[J].肝胆外科杂志，2015，23（3）：184-186.
[9]	余漪，周福平，郭玲玲，等.术后肝功能指标对肝内胆管癌根治性切除患者预后的影响[J].第二军医大学学报，2015，36（6）：627-633.
[10]	唐羿，潘凤莲.术前减黄治疗对肝门胆管癌手术效果的影响[J].解放军医药杂志，2016，21（2）：59-61.
[11]	张辉，张振，张海涛，等.肝门部胆管癌根治术前经内镜鼻胆管引流和经皮经肝胆管造影引流术的临床效果观察[J].腹部外科，2017，30（3）：197-201.
[12]	朱倩，乔国梁，晏建军，等.可切除肝门部胆管癌预后影响因素分析[J].中华肝胆外科杂志，2014，20（9）：662-666.
[13]	朱峰，王敏，彭丰，等.肝门部胆管癌术前减轻黄疸对外科治疗的影响[J].中华消化外科杂志，2013，12（3）：210-212.
[14]	王有枝，黄金华，张天奇，等.术前选择性肝内胆道引流减黄治疗对肝门部胆管癌手术患者预后的影响[J].海南医学，2018，27（1）：47-49.
[15]	张雅敏.肝门部胆管癌的术前减黄与术后难治性感染的关系[J].国际外科学杂志，2016，43（4）：167-169.