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Changes of hemorheological and platelet-related parameters in women with pregnancy-induced hypertension |
XU Yan-lei MI Mei-yan ZHANG Jun-na QIANG Zhe |
Department of Gynecology and Obstetrics,the Fourth Hospital of Shijiazhuang City,Hebei Province,Shijiazhuang 050000,China |
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Abstract Objective To analyze the changes of hemorheological and platelet-related parameters in women with pregnancy-induced hypertension.Methods A total of 90 pregnant women with gestational hypertension were selected and equally divided into three groups according to different disease conditions:severe preeclampsia group,preeclampsia group,pregnancy-induced hypertension group,30 cases in each group.Another group of 30 pregnant women with late pregnancy were classified into normal late pregnancy group during the same period.The cases were collected was from January 2,2015 to February 10,2016.The hemorheological and platelet-related parameters in pregnant women from different groups were analyzed.Results The erythrocyte aggregation index (EAI),K value of erythrocyte sedimentation rate(ESR),low-sheared reduction viscosity,and low-sheared viscosity of whole blood in the severe preeclampsia group were all higher than those in the other three groups with significant differences(P<0.05).The EAI in the pregnancy-induced hypertension group was higher than the normal late pregnancy group and the preeclampsia group with statistical significance(P<0.05).In the normal late pregnancy group,platelet distribution width and mean platelet volume were lower than those in the other three groups with statistical differences (P<0.05).The platelet count was lower in the normal late pregnancy group than that in the pregnancy-induced hypertension group with a significant difference(P<0.05).Conclusion There are abnormal platelet and hemorheological changes in women with pregnancy-induced hypertension.The indexes mentioned above are of great significance for the prevention and treatment of hypertensive disorders during pregnancy as well as its monitoring.
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[1] |
Rahim R,Nahar K,Khan IA.Platelet count in 100 cases of pregnancy induced hypertension[J].Mymensingh Med J,2010,19(1):5,9.
|
[2] |
赵映华,吴雪琴,何勤径,等.妊娠期高血压疾病孕妇凝血功能的对照研究[J].海南医学,2013,24(17):2522-2524.
|
[3] |
周利娟.妊娠期高血压疾病患者凝血指标及血小板参数测定的临床价值[J].中外医疗,2013,32(20):40,43.
|
[5] |
华杰.妊娠期高血压疾病患者凝血功能及抗氧化能力的变化及临床意义[J].中国妇幼保健,2016,31(2):266-268.
|
[6] |
刘洋,徐梅,蒋英,等.血清微量元素及抗氧化能力指标与妊娠期高血压疾病的关系分析[J].海南医学院学报,2016,22(6):574-576.
|
[7] |
姜玲.血小板活化指标及脂代谢指标与妊娠高血压疾病的相关性[J].实用临床医药杂志,2017,21(1):81-83.
|
[4] |
Biodcau JF.Review:maternal and placental antioxidant response topreeclampsia-impact on vasoactive eicosanoids[J].Placenta,2014,35(Suppl):s32-38.
|
[8] |
穆启霞.妊娠期高血压疾病化验指标的临床意义分析[J].中国保健营养,2014,24(4):2604-2605.
|
[9] |
韩艳君,张满凤,李艳,等.妊娠期高血压疾病与血小板降低及子宫动脉血流异常的相关性[J].山西医药杂志,2016,45(1):14-16.
|
[10] |
冯燕,徐军娟.妊娠期高血压疾病患者凝血功能及血小板参数变化与疾病严重程度的相关性分析[J].中国妇幼保健,2016,31(5):947-948.
|
[11] |
傅向红,夏星璐,夏建妹,等.妊娠期高血压疾病凝血指标及血脂变化的临床研究[J].中国现代医生,2016,54(7):16-18.
|
[12] |
赵昆,向巴曲西,容文辉,等.西藏高原地区重度子痫前期患者血小板和凝血指标变化分析及临床意义[J].吉林医学,2017,38(12):2217-2219.
|
[13] |
胡艳红,徐忠芳.妊娠期高血压疾病产妇围生期血液黏度与血小板参数的变化研究[J].中国医学创新,2016,13(19):95-97.
|
[14] |
杨淑莉,司丽慧,范丽梅,等.妊娠期高血压疾病患者血液指标的改变及临床意义[J].中国妇幼保健,2015,30(27):4622-4623.
|
[15] |
林丽珍,杨茵,葛榕,等.妊娠期高血压疾病孕妇血液流变学及血小板相关参数的变化[J].福建医药杂志,2014,36(4):81-83.
|
|
|
|