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Effect of Huangqi Yiqi Decoction combined w ith western medicine in patients w ith chronic atrophic gastritis |
LIANG Wan-ning1 HOU Yan-ping2 QIAN Cai-feng3 MEI Quan-xi4 |
1.Department of Pharmacy,Guangdong Province,Zhaoqing 526040,China;
2.Department of Digestive Internal Medicine,People′s Hospital of Gaoyao District in Zhaoqing City,Guangdong Province,Zhaoqing 526040,China;
3.Departmentof Traditional Chinese Medicine,People′s Hospital of Gaoyao District in Zhaoqing City,Guangdong Province,Zhaoqing 526040,China;
4.Department of Pharmacy,People′s Hospital of Zhongshan City,Guangdong Province,Zhongshan 528401,China |
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Abstract ObjectiveTo investigate the effect of Huangqi Yiqi Decoction combined with western medicine in the treatment patients with chronic atrophic gastritis.MethodsEighty-five patients with chronic atrophic gastritis admitted to People′s Hospital of Gaoyao District in Zhaoqing City from March 2014 to January 2017 were selected as study subjects and randomly divided into:observation group(42 cases)and control group(43 cases).Patients in the control group were treated with Omeprazole,Colloidal Pectin Bismuth and Amoxicillin on the basis of general treatment.The patients in the observation group were given Huangqi Yiqi Decoction,Omeprazole and Colloidal Pectin Bismuth on the basis of general treatment.The total effective rate of clinical curative effect,the total effective rate of gastroscope curative effect,the clearance rate of Helicobacter Pylori infection,the biopsy pathology and the quantification of chronic atrophic gastritis symptoms were observed.ResultsAfter treatment,the total effective rate of clinical curative effect,the total effective rate of gastroscopy,the total effective rate of biopsy pathological treatment was higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in HP infection clearance between the two groups(P>0.05).After treatment and follow-up six months,the observation group of patients with chronic atrophic gastritis symptom score were lower than the control group,the difference was statistically significant(P<0.01).ConclusionHuangqi Yiqi Decoction combined with western medicine can effectively improve the clinical symptoms of patients with chronic atrophic gastritis,have a certain role in eradicating HP infection,and the long-term effect is good,worthy of clinical promotion.
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[6] |
房静远,刘文忠,李兆申,等.中国慢性胃炎共识意见[J].胃肠病学,2013,18(1):24-36.
|
[7] |
梁茂新,高天舒.《中药新药临床研究指导原则》脏腑诸证考察与分析[J].中国中医基础医学杂志,2008,14(5):330-331.
|
[8] |
张万岱,陈治水,危北海.慢性胃炎的中西医结合诊治方案(草案)[J].中国中西医结合学会全国消化系统疾病学术研讨会[C],2003,(2):172-175.
|
[9] |
赵冰,肖淑萍,顾敏,等.慢性萎缩性胃炎的危险因素及以叶酸为主治疗方案的疗效观察[J].中华消化杂志,2013,33(11):768-769.
|
[10] |
丁成华,李晶晶,方芳,等.慢性萎缩性胃炎中医病机与证候分布规律研究[J].中华中医药杂志,2011,26(3):582-586.
|
[5] |
梁大铭,孔华云,翁蓉蓉,等.毛水泉教授治疗慢性萎缩性胃炎经验辑要[J].浙江中医药大学学报,2017,41(6):506-508.
|
[1] |
Chen XZ,Schottker B,Castro FA,et al.Association of helicobacter pylori infection and chronic atrophic gastritis with risk of colonic,pancreatic and gastric cancer:a ten-year follow-up of the ESTHER cohort study[J].Oncotarget,2016,7(13):17182-17193.
|
[2] |
Boyce M,Moore AR,Sagatun L,et al.Netazepide,a gastrin/cholecystokinin-2 receptor antagonist,can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis[J].Br J Clin Pharmacol,2017,83(3):466-475.
|
[11] |
刘姗姗,徐丘卡,陈锐,等.麦滋林颗粒联合间苯三酚注射液治疗孕妇急性胃炎疗效观察[J].中国药师,2015,18(4):602-603.
|
[12] |
廖纬琳,陈国忠,夏李明.半夏泻心汤治疗慢性萎缩性胃炎的 meta 分析[J].时珍国医国药,2014,25(6):1526-1529.
|
[13] |
边平达,寿张轩.阿仑膦酸钠片致老年女性骨质疏松症患者癌胚抗原轻度增高 1 例[J].中国药师,2016,19(4):702-703.
|
[14] |
刘婷,苏泽琦,刘福生,等.调气活血法治疗大鼠慢性萎缩性胃炎的疗效观察及其影响胃酸分泌的机制[J].中华中医药杂志,2016,31(10):4176-4179.
|
[3] |
Gao X,Zhang Y,Brenner H.Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults[J].Br J Cancer,2017,117(8):1211-1214.
|
[4] |
Huang J,Zagai U,Hallmans G,et al.Helicobacter pylori:a nested case-control study infection,chronic corpus atrophic gastritis and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition(epic) cohort:a nested case-control study[J].Int J Cancer,2017,140(8):1727-1735.
|
[15] |
陈庆,魏睦新.魏睦新教授辨证与辨病结合治疗萎缩性胃炎经验撷要[J].辽宁中医药大学学报,2013,15(3):97-99.
|
[16] |
杨远姗,卢凤立,李翠勤.泮托拉唑钠联合艾灸治疗慢性浅表性胃炎的疗效观察[J].药物流行病学杂志,2017,12(11):739-741.
|
[17] |
俞芹,黄海芹,曹力,等.中医药治疗Hp相关性胃炎思路与方法[J].辽宁中医药大学学报,2012,14(10):87-88.
|
[18] |
赵越,彭海英.雷贝拉唑联合胃康胶囊治疗胃炎疗效观察[J].药物流行病学杂志,2017,21(1):17-18.
|
[19] |
杨丁友.土茯苓治疗慢性萎缩性胃炎[J].中医杂志,2002,43(10):732.
|
[20] |
胡玉翠,周晓波.慢性萎缩性胃炎的中医证治概述[J].长春中医药大学学报,2017,33(3):507-510.
|
[21] |
苏泽琦,于春月,张文君,等.国医大师路志正治疗慢性萎缩性胃炎临证经验[J].现代中医临床,2017,24(3):34-36.
|
|
|
|